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Jai Radhe Sales
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Active Pharmaceutical Ingredients 1

Providing you the best range of erythromycin sterate, donepezil hcl, dopamine hcl, doxapram hcl, doxylamine succinate and drotaverine hcl with effective & timely delivery.

Erythromycin Sterate

Erythromycin Sterate
  • Erythromycin Sterate
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Dosage FormPowder
CAS Number643-22-1
IUPAC Name(2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-11
Molecular FormulaC55H103NO15
ApplicationMacrodiles antibacterial

Erythromycin Stearate is a macrolide, acid labile compound derived from Erythromcyin. Erythromycin is a potent macrolide inhibitor of CYP3A4 with anti-inflammatory and prokinetic properties. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Mouse studies show Erythromycin Stearate increases IL-1 and IL-2 levels.

Synonyms:
  • oe7; Wemid; ethril; erypar; Ethryn; eratrex; meberyt; Eryprim; pfizer-e; qidmycin

 

IUPAC Name:

  • 11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-5-ethyl-3,4,12-trihydroxy-9-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-2,4,8,10,12,14-hexamethyl-6-oxacyclotetradecane-1,7-dione; octadecanoic acid
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Donepezil HCL

Donepezil HCL
  • Donepezil HCL
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IUPAC Name2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]- 1H-inden-1-one hydrochloride
CAS Number120011-70-3
Molecular FormulaC24H29NO3.HCL
ApplicationAntialzheimer

White crystalline powder

Synonyms:
  • 2,3-Dihydro-5, 6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]-1H-inden-1-one; 2-(1-Benzyl-4-piperidylmethyl)-5, 6-dimethoxy-1-indanone Hydrochloride
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Dopamine HCL

Dopamine HCL
  • Dopamine HCL
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IUPAC Name4-(2-aminoethyl)benzene-1,2-diol
CAS Number335081-04-4
Molecular FormulaC8H12CINO2
ApplicationCardio Tonic

Off white crystalline powder, can occur in mild hydrochloric acid smell, melts at about 240˚C, with decomposition

Synonyms:
  • 2-(3,4-Dihydroxyphenyl)Ethyl-1-13C-Amine Hcl; 3,4-Dihydroxyphenyl-Ethylamine Hydrochloride; 3,4-Dihydroxyphenethylamine, Hcl; 4-(2-Aminoethyl)-1-2-Benzenedial Hydrochloride; 4-(2-Aminoethyl)Pyrocatechol Hydrochloride; 3-Hydroxytyraminium Chloride; Hydroxytyramine Hcl; Labotest-Bb Lt00233111
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Doxapram HCL

Doxapram HCL
  • Doxapram HCL
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IUPAC Name1-Ethyl-4-[2-(4-Morpholinyl)Ethyl]-3,3-Diphenyl-2-Pyrrolidinone Hydrochloride
CAS Number113-07-5
Molecular FormulaC24H31CIN2O2
ApplicationAnaesthetics

White to off white odourless crystalline powder, Melts at about 220˚C

Synonyms:
  • 3,3-Diphenyl-1-Ethyl-4-(2-Morpholinoethyl)-2-Pyrrolidinone Hydrochloride
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Doxylamine Succinate

Doxylamine Succinate
  • Doxylamine Succinate
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IUPAC NameN,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine Succinate
CAS Number562-10-7
Molecular FormulaC21H28N2O5
ApplicationAntihistaminic

White, odorless powder. Very soluble in water and in alcohol, freely soluble in . Very slightly soluble in ether and in Benzene

Synonyms:
  • Unisom; Hoggarn; Decapryn; Alsadorm; Gittalun; Sedaplus; Mereprine; Decapryn Succinate; Doxylaminesuccinat; Doxylamine Succinate
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Drotaverine HCL

Drotaverine HCL
  • Drotaverine HCL
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IUPAC Name(1Z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-3, 4-dihydro-2H-isoquinoline
CAS Number985-12-6
Molecular FormulaC24H32ClNO4
ApplicationA papaverine analog

Drotaverine Hydrochloride is an antispasmodic, and an analogue of Papaverine.

Synonyms:
  • 1,2,3,4-Tetrahydro-6,7-diethoxy-1-((3,4-diethoxyphenyl) methylene)-isoquinoline hydrochloride
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Duloxetine HCL

Duloxetine HCL
  • Duloxetine HCL
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IUPAC Name(+)-(S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine
CAS Number136434-34-9
Molecular FormulaC18H19NOS. HCL
ApplicationAntidepressant

Duloxetine HCl is used to treat major depression—a disorder marked by continuing, serious, and overwhelming feelings of depression that interfere with daily functioning. Symptoms may include major changes in appetite or sleep habits; lack of interest in social or work life; feelings of sadness, guilt, or worthlessness; fatigue; difficulty concentrating or making decisions; and suicidal thoughts or attempted suicide. Duloxetine HCl is also used to treat diabetic peripheral neuropathy, a painful nerve disorder associated with diabetes that affects the hands, legs, and feet. Duloxetine HCl is thought to work by correcting an imbalance of two brain chemicals known to influence mood—serotonin and norepinephrine. It belongs to a class of antidepressants called selective serotonin and norepinephrine reuptake inhibitors.

Synonyms:
  • N-Methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine
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Eosin Disodium

Eosin Disodium
  • Eosin Disodium
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IUPAC NameDisodium 2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate
CAS Number17372-87-1
Molecular FormulaC20H6BR4NA2O5
ApplicationAnti Septic

Brownish Red Powder.

Synonyms:
  • 2na; bromob; eosina; RED 22; Red A; bromo4d; bromofl; bromots; bromoxx; dawnred
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Erthromycin Base

Erthromycin Base
  • Erthromycin Base
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Molecular FormulaC37H67NO13
IUPAC Name(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6
CAS Number114-07-8
Dosage Form Powder

Erythromycin is a macrolide antibiotic produced by Streptomyces erythreus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits; binding inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. Erythromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.

Synonyms:
  • (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione

Application:
  • For use in the treatment of infections caused by susceptible strains of microorganisms in the following diseases: respiratory tract infections (upper and lower) of mild to moderate degree, pertussis (whooping cough), as adjunct to antitoxin in infections due to Corynebacterium diphtheriae, in the treatment of infections due to Corynebacterium minutissimum, intestinal amebiasis caused by Entamoeba histolytica, acute pelvic inflammatory disease caused by Neisseria gonorrhoeae, skin and soft tissue infections of mild to moderate severity caused by Streptococcus pyogenes and Staphylococcus aureus, primary syphilis caused by Treponema pallidum, infections caused by Chlamydia trachomatis, nongonococcal urethritis caused by Ureaplasma urealyticum, and Legionnaires' disease caused by Legionella pneumophila.

 

IUPAC Name:

  • {[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}- 14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)- 5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}- 3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
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Erythromycin Ethyl Succinate

Erythromycin Ethyl Succinate
  • Erythromycin Ethyl Succinate
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IUPAC Name1-O-[4-(dimethylamino)-2
CAS Number41342-53-4
Molecular FormulaC43H75NO16
ApplicationA preparation of the widely used antibiotic Erythromycin.

Erythromycin Ethylsuccinate exhibits antibiotic properties.

Synonyms:
  • Aids007905; Aids-007905;Erythromycin 2'-(Ethyl Succinate); 2'-(Ethyl Butanedioate)Erythromycin; Erythromycin 2'-(Ethyl Butanedioate); Erythromycin Ethyl Succinate - Bp/Ep/Usp 1264-62-6

 

IUPAC Name:

  • [[(1R,2R,4R,6R,7R,8S,9R,12R,13S)-9-ethyl-2,7,8-trihydroxy-13-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-2,4,6,8,12,14-hexamethyl-5,11-dioxo-10-oxacyclotetradec-1-yl]oxy]-6-methyloxan-3-yl] 4-O-ethyl butanedioate
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Escitalopram Oxalate

Escitalopram Oxalate
  • Escitalopram Oxalate
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CAS Number219861-08-2
IUPAC Name(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile; oxalic acid
Molecular FormulaC22H23FN2O5
ApplicationAnti-depressant

White or almost white, crystalline powder

Synonyms:
  • (S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile oxalate
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Ethambutol HCL

Ethambutol HCL
  • Ethambutol HCL
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IUPAC Name2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol
CAS Number1070-11-7
Molecular FormulaC10H24N2O2
ApplicationAntituberculous

An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect.

Synonyms:
  • (2S,2'S)-2,2'-(Ethylenediimino)dibutan-1-ol dihydrochloride
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Ezetimbe Powder

Ezetimbe Powder
  • Ezetimbe Powder
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Molecular FormulaC24H21F2NO3
IUPAC Name(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2
CAS Number163222-33-1
MetabolismIntestinal wall

Ezetimibe is an anti-hyperlipidemic medication which is used to lower cholesterol levels. Specifically, it appears to bind to a critical mediator of cholesterol absorption, the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelial cells as well as in hepatocytes.

Synonyms:
  • ZETIA; Ezitimibe??? EzetimibeC24H21F2N03; (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone, Sch-58235; 1-(4-Flurophenyl)-(3R)-3-(4-flurophenyl)-(3S)-hydroxypropyl-(4S)-(4-hydroxyphenyl)-2-azetidinone; Ezetimide; (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one

 

Application:

  • For use as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and non-familial) hypercholesterolemia.
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Etoricoxib Powder

Etoricoxib Powder
  • Etoricoxib Powder
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IUPAC Name5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]- 2,3'-bipyridine
CAS Number202409-33-4
Molecular FormulaC18H15CIN2O2S
Molar mass358.842 g/mol

Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2). This reduces the generation of prostaglandins (PGs) from arachidonic acid.

Synonyms:
  • Algix; Etoxib; Etocox; MK 663; Tauxib; Etobrix; Arcoxia; Kingcox; MK 0663; Etropain

 

Application:

  • For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
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    Febuxostat Powder

    Febuxostat Powder
    • Febuxostat Powder
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    Molecular FormulaC16H16N2O3S
    IUPAC Name2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid
    CAS Number144060-53-7
    ApplicationFebuxostat is primarily indicated in conditions like Gout, Hyperuricemia.

    Febuxostat belongs to a group of drugs known as xanthine oxidase (XO) inhibitors. It is used to reduce blood uric acid levels in patients with gout, a painful arthritic condition that mainly affects the big toe, but can also affect the ankles, heels, knees, elbows, wrists or fingers.Febuxostat is used in the treatment of gout patients with hyperuricemia, or high uric acid levels.The most common side effects of Uloric are liver problems,nausea,joint pain.

    Synonyms:
    • Fbx; Uloric; Tmx 67; Tei-6720; Febuxosta; Febuxostat; Febuxostat Api; Febuxostat Tablets; Febuxostat (Uloric); Febuxostat (Tei-6720)
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    Fenofibrate Powder

    Fenofibrate Powder
    • Fenofibrate Powder
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    IUPAC Namepropan-2-yl 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoate
    CAS Number49562-28-9
    Molecular FormulaC20H21CIO4
    ApplicationCardiovascular disease

    An antilipemic agent which reduces both cholesterol and triglycerides in the blood.

    Synonyms:
    • lf-178; lipsin; lipifen; lipidax; sedufen; LIPYDIL; Lipirex; Liposit; Nolipax; Secalip
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    Fenticonazole Nitrate

    Fenticonazole Nitrate
    • Fenticonazole Nitrate
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    IUPAC Name1-[2-(2,4-dichlorophenyl)-2-[(4-phenylsulfanylphenyl)methoxy]ethyl]imidazole; nitric acid
    CAS Number73151-29-8
    Molecular FormulaC24H20CI2N2OS
    ApplicationAnti fungal

    Fenticonazole Nitrate is an azole antifungal drug that inhibits CYP51A1 (14 α-demethylase) and ergosterol production. It shows active effects against Malassezia furfur and Candida albicans in vivo.

    Synonyms:
    • 1-[2-(2,4-dichlorophenyl)-2-[[4-(phenylthio)phenyl]methoxy]ethyl]-1H-imidazolium nitrate; Fenticonazol Nitrate; 1-[2-(2,4-Dichlorophenyl)-2-[(4-phenylsulfanylphenyl)methoxy]ethyl]imidazole nitrate; 1-[2-(2,4-Dichlorophenyl)-2-[[4-(phenylthio)phenyl]methoxy]ethyl]-1H- imidazole mononitrate; Falvin; Fentiderm; Fentigyn; Lomexin; Rec-15―1476; 1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)benzyl]oxy}ethyl]-1H-imidazole nitrate (1:1); 1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)benzyl]oxy}ethyl]-1H-imidazole
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    Ferrous Fumarate

    Ferrous Fumarate
    • Ferrous Fumarate
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    IUPAC Name(E)-But-2-enedioate; iron(2+)
    CAS Number141-01-5
    Molecular FormulaC4HFEO4
    ApplicationNutraceutical/Minerals

    Reddish Orange or Reddish Brown Powder

    Synonyms:
    • Fumaric acid ferrous salt, iron (II) fumarate
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    Fexofenadine HCL

    Fexofenadine HCL
    • Fexofenadine HCL
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    IUPAC Name2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid hy
    CAS Number138452-21-8
    ApplicationAnti-histamine
    Molecular FormulaC32H40CI NO4

    Fexofenadine HCl, an active metabolite of terfenadine, has demonstrated to be a nonsedating Histamine H1 receptor antagonist. Mechanistic studies have reported that high concentrations of this compound can inhibit Cox-1 activity while low concentrations of Fexofenadine HCl inhibits Cox-2 activity.

    Synonyms:
    • Fexofendine Hcl; Fexofenadine Hcl; Fexofenadine Hydrochloride (200 Mg); Terfenidine Carboxylate Hydrochloride; Carboxyterfenadine, Terfenadinecarboxylate; Fexofenadine Hydrochloride (200 Mg)F1E2890.996Mg/Mg(Ai); 2-[4-[1-Hydroxy-4-[4-(Hydroxy-Diphenyl-Methyl)-1-Piperidyl]-Butyl]Phenyl]-2-Methyl-Propanoic Acid Hydrochloride; Alpha,Alpha-Dimethyl-4-[1-Hydroxy-4-[4-(Hydroxydiphenylmethyl)-1-Piperidinyl]Butyl]-Benzeneacetic Acid Hydrochloride
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    Fluconazole Powder

    Fluconazole Powder
    • Fluconazole Powder
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    IUPAC Name2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
    CAS Number86386-73-4
    Molecular FormulaC13H12F2N6O
    ApplicationTreatment of Fungal Infections.

    Triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS

    Synonyms:
    • Fluconazole Impurity C;Fluconazole Related Compound C;fluconazole related substance EP C; fluconazole related substance USP C;1,1'-(1,3-phenylene)di-1H-1,2,4-triazole;1,1'-(1,3-Phenylene)bis-1H-1,2,4-triazole
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    Fluorescein Sodium

    Fluorescein Sodium
    • Fluorescein Sodium
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    IUPAC Namedisodium 2-(3-oxido-6-oxoxanthen-9-yl)benzoate
    CAS Number518-47-8
    Molecular FormulaC20H10NA2O5
    ApplicationA sodium salt of fluorescein

    Fluorescein sodium salt is a disodium salt of fluorescein and a noted pH sensitive fluorophore. Fluorescein sodium salt has been utilized in studies as a drug model, as a penetrating dye and also as a fluorescein tracer. Fluorescein sodium salt has also been used in vitro to quantify root dentin demineralization. Additional reported uses include microscopy, as a gain medium in dye laser use and to detect latent blood stains. Common derivatives of Fluorescein include fluorescein isothiocyanate (FITC), eosin and Rose Bengal (sc-296278) and Rose Bengal sodium salt (sc-203757)

    Synonyms:
    • Uranine; c.i.766;ful-glo; Uranine Fluorin; furanium; uranineo; F luorone; Yellow 8;S NO 880
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    Fluoxetine HCL Powder

    Fluoxetine HCL Powder
    • Fluoxetine HCL Powder
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    IUPAC NameN-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
    CAS Number59333-67-4
    Molecular FormulaC17H19ClF3NO
    ApplicationAnti Depressant

    Fluoxetine is an ST (5-hydroxytryptamine/serotonin/5-HT reuptake) inhibitor. This is a racemic mixture and both R and S enantiomers which are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Additionally, Fluoxetine is also noted to increase extracellular levels of 5-HT in several areas of the rat brain as a result of reuptake inhibition. This increase in availability of 5-HT is reported to lead to a decrease in synthesis and turnover of 5-HT.

    Synonyms:
    • Zepax; LY-110; PROZAC; SARAFEM; Alzac 20; Deproxin; DigassiM; PROZAC(R); LY-110140; Affectine
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    Fluphenazine Decanoate

    Fluphenazine Decanoate
    • Fluphenazine Decanoate
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    IUPAC Name2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
    CAS Number5002-47-1
    Molecular FormulaC32H44F3N3O2S
    ApplicationAntipsychotic

    Pale yellow, viscous liquid or yellow solid

    Synonyms:
    • 2-[4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl decanoate
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    Fluvoxamine Maleate

    Fluvoxamine Maleate
    • Fluvoxamine Maleate
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    IUPAC Name(Z)-but-2-enedioic acid;2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanami
    CAS Number61718-82-9
    Molecular FormulaC19H25F3N2O6
    ApplicationAnxiety disorder

    Fluvoxamine maleate is a selective SR (serotonin reputake) inhibitor. Fluvoxamine is described to bind the human 5-HT transporter protein with high affinity (Ki = 1.6 nM) while demonstrating very low affinity at the norepinephrine transporter (Ki = 2,950 nM). Fluvoxamine maleate is a Sigma Receptor agonist.

    Synonyms:
    • Fluvoxamine Maleate; (E)-5-Methoxy-1-[4-(Trifluoromethyl)Phenyl]-1-Pentanone-O-(2-Aminoethyl)Oxime Maleate; 1-Pentanone,5-Methoxy-1-(4-(Trifluoromethyl)Phenyl)-,O-(2-Aminoethyl)Oxime,(;5-Methoxy-4-Trifluoromethylvalerophenone(E)-O-2-Aminoethyloximemonomaleate;Du23000;Faverin50; (E)-5-Methoxy-1-[4-(Trifluoromethyl)Phenyl]-O-(2-Aminoethyl)Oxime-1-Pentanone; Mk-264, Di-23000, Dumirox, Flaverrin, Fevarin, Floxyfral, Luvox, Maveral, (E)-5-Methoxy-1-[4-(Triflurormethyl)Phenyl]-1-Pentanone, Maleate
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    Formoterol Fumarate

    Formoterol Fumarate
    • Formoterol Fumarate
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    CAS Number43229-80-7
    Molecular Formula(C19H24N2O4)2.C4H4O4.2HNO
    IUPAC NameN-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide
    ApplicationA potent Bita 2-AR agonist

    Formoterol Fumarate is shown to be a potent β-AR adrenoceptor agonist, with a fast onset of effect on the isolated human bronchus model. This compound demonstrates a 330-fold selectivity for β2 over β1 receptors. Formoterol Fumarate has been reported to be 150-200 times more potent than isoprenaline. This agent has also been noted to reduce the loss of muscle mass in murine models.

    Synonyms:
    • Ym 08316; Cgp 25827A; Nsc 299587; Farmeterol; Aformoterol; Cgp-25827A-E; Formoterol Fumarate; Formaterol Fumatate; Formaterol Fumarate; Eformoterol Fumarate
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    Fosphenytoin Sodium

    Fosphenytoin Sodium
    • Fosphenytoin Sodium
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    IUPAC NameDisodium [2,5-dioxo-4,4-di(phenyl)imidazolidin-1-yl]methyl phosphate
    CAS Number92134-98-0
    Molecular FormulaC16H13N2Na2O6P
    ApplicationAnti epileptic

    Prodrug of phenytoin that converts to the anticonvulsant, phenytoin, after parenteral administration. Thought to modulate the sodium channels of neurons, calcium flux across neuronal membranes, and enhance the sodium–potassium ATPase activity of neurons and glial cells. The cellular mechanism of phenytoin is thought to be responsible for the anticonvulsant activity of fosphenytoin. Control of generalized convulsive status epilepticus and the prevention and treatment of seizures during neurosurgery, or as a parenteral short-term substitute for oral phenytoin.

    Synonyms:
    • Ci 982; Cetebyx; Acc-9653; Fospenytoin; Acc 9653-010; Pro-Epanutin; Fosphenytion Sodium; Fosphenytoin Sodium; Fosphenytoin Sodium Usp; Fosphenytoin Disodium Salt
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    Frusemide Powder

    Frusemide Powder
    • Frusemide Powder
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    IUPAC Name4-chloro-2-(furan-2-ylmethylamino)- 5-sulfamoylbenzoic acid
    CAS Number54-31-9
    Molecular FormulaC12H11CINNO5S
    MetabolismLiver and kidney glucuronidation

    A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for edema and chronic renal insufficiency. For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Also for the treatment of hypertension alone or in combination with other antihypertensive agents.

    Synonyms:
    • 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid; 4-chloro-n-furfuryl-5-sulfamoylanthranilic acid; 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid; Frusemide

     

    Application:

    • This compound belongs to the aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
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    Sumatriptan Succinate

    Sumatriptan Succinate
    • Sumatriptan Succinate
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    IUPAC Name1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide
    CAS Number103628-48-4
    Molecular FormulaC18H27N3O6S
    ApplicationA selective 5-HT1 receptor agonist

    Sumatriptan succinate is a selective 5-HT1 receptor agonist with specificity towards 5-HT1D, 5-HT1B and 5-HT1A. In addition, the physicochemical properties of Sumatriptan succinate can be characterized using FT-IR, HPLC, SEM and XRD. It has been reported that Sumatriptan succinate can be produced via reactive precipitation without the presence of surfactants. Further studies show that molecules of Sumatriptan succinate are carried through cells using liposomes, with positively charged liposomes exhibiting the highest loading efficiency.

    Synonyms:
    • Gr43175C; Sumitrex; Sumatriptan Succinate; Methanesulfonamide(1:1); Sumatriptan Succinate, Ep;Sumatriptansuccinate(1:1); Sumatriptan Succinate (200 Mg); 3-[2-(Dimethylamino) Ethyl]-N-Methyl-1H-Indole-5-Methane Sulfonamide; Compd.With3-(2-(Dimethylamino)Ethyl)-N-Methyl-1H-Indole-5-Butanedioicaci; 3-[2-(Dimethylamino)Ethyl]-1H-Indol-5-Yl-N-Methylmethanesulfonamide Succinate
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    Tamsulosin HCL

    Tamsulosin HCL
    • Tamsulosin HCL
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    IUPAC Name5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
    CAS Number106463-17-6
    Molecular FormulaC20H28N2O5S.HCL
    ApplicationAn Alpha 1-adrenoceptor antagonist

    Tamsuolosin Hydrochloride is an α1A-AR (α1-adrenoceptor) antagonist commonly used to treat benign prostatic hypertrophy. Tamsulosin hydrochloride has shown possible usefulness in suppressing central sympathetic hyperactivity in amyotrhophic lateral sclerosis Tamsulosin Hydrochloride is an inhibitor of α1B-AR.

    Synonyms:
    • Omic; Omnic; Pradif; Ym-617; Flomax; Harnal; Yutana; Yutanal; LY-253351; Ym-12617-1
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    Dorzolamide HCL

    Dorzolamide HCL
    • Dorzolamide HCL
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    IUPAC Name4H-Thieno[2,3-b]thiopyran-2-sulfonamide,4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, hydrochlo
    CAS Number130693-82-2
    Molecular FormulaC10H16N2O4S3, HCl

    This drug is an eye medication that is used in dogs and cats to decrease the pressure in the eye. It is available in the form of drops.

    Synonyms:
    • Rac-trans Dorzolamide; 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5, 6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, trans-; 4H-Thieno[2,3-b]thiopyran-2-sulfonaMide,4-(ethylaMino)-5, 6-dihydro-6-Methyl-, 7, 7-dioxide, hydrochloride (1:1), (4R,6R)-rel

     

    Application:

    • Dorzolamide HCl Ophthalmic Solution is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
       
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      Tacrolimus Powder

      Tacrolimus Powder
      • Tacrolimus Powder
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      MetabolismHepatic CYP3A4, CYP3A5
      CAS Number104987-11-3
      Molecular FormulaC44H69NO12

      acrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient’s immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.

      Synonyms:
      • FK-506; prograf; fr900506; L 679934; Protopic; Advagraf; Fujimycin; TacroBell; TACROLIMUS; FK-506, 99+%

      Application:
      • For use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart, small bowel, pancreas, lung, trachea, skin, cornea, and limb transplants. It has also been used in a topical preparation in the treatment of severe atopic dermatitis.

      IUPAC Name:
      • (1R,9S,12S,13R,14S,17R,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone
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