Active Pharmaceutical Ingredients 4

Product Details:

Cabergoline is used to treat different types of medical problems that occur when too much of the hormone prolactin is produced. It can be used to treat certain menstrual problems, fertility problems in men and women, and pituitary prolactinomas (tumors of the pituitary gland).
CABERGLINE USP JAIRADHE SALES CABERGLINE USP JAIRADHE SALES

Product Details:

An adrenergic vasoconstrictor agent used as a decongestant.

IUPAC name - 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole;hydrochloride

 

Product Details:

Pantoprazole Sodium is a gastic proton pump inhibitor.

 

Synonyms:

• Pantoprozole soclium Ph.Eur; PantoprozoleSodium; sodium 5-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide; [5-(difluoromethoxy)-2-[(3,4-dimethoxy-2-pyridyl)methylsulfinyl]benzimidazol-1-yl]sodium; 5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl) sulfinyl)-1H-benzimidazole sodium

 

IUPAC Name:

• Sodium 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1,2-dihydrobenzimidazol-3-ide hydrate

Product Details:

White, Odorless Crystalline Powder

 

Synonyms:

• jumex; FP-OD; fpf1100; Amindan; Anipryl; eldepryl; Movergan; Plurimen; Eldeprine; Selegiline

SELEGILINE HCL JAIRADHE SALES

Product Details:

A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.

Synonyms:

• Dorme; Phena; atosil; hl8700; remsed; ganphen; phencen; plletia; primine; promine

PROMETHAZINE HCL JALRADHESALES

Product Details:

Sertraline HCl is a selective and potent inhibitor of ST (serotonin transporter), increasing availability of serotonin in the brain. Sertraline displays antiproliferative activity on human colorectal carcinoma cells.

Synonyms:

• Cp-51974-1; Setraline Hcl; (1S-Cis)-Lorid;Lustral: Zoloft;Sertraline Mandelate; Sertraline Hydrochlo; Sertraline Hcl Form I; Sertraline Hcl Form Ii; Sertaline Hydrochloride; Sertraline Hydrochloride

Product Details:

Pyrazinamide is an antibacterial agent used to form polymeric copper complexes. It is also useful for studying liver toxicity prevention. Further, the active moiety of pyrazinamide, pyrazinoic acid (POA), is believed to interfere with membrane energetics and transport function in Mycobacterium tuberculosis.

Product Details:

White or almost white crystalline powder

 

Synonyms:

• (+-)-y; dl-albuterol; r,s-albuterol; dl-salbutamol; Racemic-salbutamol; 1-(4-hydroxy-3-hydroxymethylphenyl)-2-(tert-Butylamino)-ethanol-1; (+-)-alpha(sup1)-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-1,3-benzenedim; (+-)-alpha(Sup 1)-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-1,3-benzenedimethanol; 1,3-Benzenedimethanol, alpha(sup 1)-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, (+-)

Product Details:

Propranolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension.

Synonyms:

• (Rs)-1-[(1-Methylethyl)Amino]-3-(1-Naphthalenyloxy)-2-Propanol Hydrochloride; Propranolol Hcl; (+/-)-Propranolol Hydrochloride; Propranolol Hydrochloride; (+/-)-Propanolol Hcl;Propanolol Hydrochloride; 1-((1-Methylethyl)Amino)-3-(1-Naphthalenyloxy)-2-Propanohydrochloride; 1-(1-Naphthyloxy)-2-Hydroxy-3-Isopropylaminopropanehydrochloride

Product Details:

White crystalline powder.

IUPAC name: Sodium hydroxy-(1-hydroxy-1-phosphono-2-pyridin-3-ylethyl)phosphinate

 

Synonyms:

• Actonel; Ne 58095; Risedronate Na; Risedronate, Rid;Risedronat Sodium; Risedremate Sodium; Sodium Risedronate; Risedronate Sodium; Risendronate Sodium; Risedronatesodium&Int.

Product Details:

An off white to creamish white powder

 

Synonyms:

• (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[N-methyl(n-methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-Heptenoic calcium; (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid; calcium(-1) anion; (E)-6-[4-(4-fluorophenyl)-6-isopropyl-2-(methyl-methylsulfonyl-amino)pyrimidin-5-yl]-2,4-dihydroxy-hex-5-enoate; Rosuvastatin Calcium

 

IUPAC Name:

• Calcium (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate

 

Product Details:

Silodosin is an orally available, alpha-1 adrenoceptor antagonist that is selective for the prostate. Silodosin is for symptomatic treatment of benign prostatic hyperplasia. FDA approved Oct 9, 2008.Silodosin is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist.

IUPAc name - 1-(3-hydroxypropyl)-5-[(2R)-2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]-2,3-dihydroindole-7-carboxamide

Product Details:

An anthelmintic used in most schistosome and many cestode infestations.

IUPAC name - 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one

Product Details:

This compound belongs to the polyamines. These are compounds containing more than one amine group.

 

Synonyms:

• 2-Propylpentanoic acid; Dipropylacetic acid; 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone; 2-propylpentanoic acid

 

Application:

• For treatment and management of seizure disorders, mania, and prophylactic treatment of migraine headache. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, and the seizures associated with Lennox-Gastaut syndrome.

Product Details:

Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonase®. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymista. Dymista is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.

Synonyms:

• S-Fluoromethyl-6Alpha,9Alpha-Difluoro-11Beta-Hydroxy-16Alpha-Methyl-3-Oxo-17Alpha-Propionyloxyandrosta-1,4-Diene-17Beta-Carbothioate;-17-(1-Oxopropoxy)-,S-(Fluoromethyl)Ester,(6-Alpha,11-Beta,16-Alpha,17-Alph;Androsta-1,4-Diene-17-Carbothioicacid,6,9-Difluoro-11-Hydroxy-16-Methyl-3-Oxo;Cci18781;Fluticasone17-Propionate;Flutide; (6A,11B,16A,17A)-6,9-Difluoro-11-Hydroxy-16-Methyl-3-Oxo-17-(1-Oxopropoxy)Androsta-1,4-Diene-17-Carbothioic Acid Fluoromethyl Ester; (6 Alpha,11 Beta,16 Alpha,17 Alpha)-6,9-Difluoro-11-Hydroxy-16-Methyl-3-Oxo-17-(1-Oxopropoxy)Androsta-1,4-Diene-17-Carbothioic Acid Fluoromethyl Ester

Product Details:

Nitazoxanide, also known by the brand name Alinia, is a synthetic nitrothiazolyl-salicylamide derivative and an anti-protozoal agent. It is approved for treatment of infectious diarrhea caused by Cryptosporidium parvum and Giardia lamblia in patients 1 year of age and older. Following oral administration it is rapidly hydrolyzed to its active metabolite, tizoxanide, which is 99% protein bound. Peak concentrations are observed 1–4 hours after administration. It is excreted in the urine, bile and feces. Untoward effects include abdominal pain, vomiting and diarrhea.

Application:

• For the treatment of diarrhea in adults and children caused by the protozoa Giardia lamblia and for the treatment of diarrhea in children caused by the protozoa Cryptosporidium parvum.

Product Details:

Naloxone hydrochloride is a nonspecific receptor antagonist that displays anitnociceptive effects. Studies have identified this product as a significant immunoadjuvant in cancer immunotherapy. Reportedly exhibits the ability to reverse various types of cardiovas Naloxone hydrochloride is an inhibitor of DOR, KOR, MOR and Sigma Receptor.

Synonyms:

• (5α)-17-allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride

Product Details:

This compound belongs to the diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.

Synonyms:

• Meclizine Hydrochloride (500 MG); Meclizine hydrochloride; Antivert; Permesin; Meclizine Hydrochloride Monohydrate; Meclizine dihydrochloride monohydrate; 1-[(4-Chlorophenyl)phenylMethyl]-4-[(3-Methylphenyl)Methyl]piperazine DiHydrochloride Hydrate; Meclizine Related CoMpound B

 

IUPAC Name:

• 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine; hydrate;dihydrochloride

 

 

Product Details:

 Ciclopirox olamanie is used to treat fungal skin infections such as athlete's foot, jock itch, and ringworm. This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs.

Product Details:

A white or almost white, Hygroscopic powder

Synonyms:

• Omeprazole Sodium; Omeprazole, sodium salt; Omeprazole powder/pellets/sodium; odiuM 5-Methoxy-2-[(4-Methoxy-3,5-diMethyl-pyridin-2-yl)Methylsulfinyl]benzoiMidazole; sodium 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]benzoimidazole; 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1h-benzimidazole sodium salt

Product Details:

Orphenadrine Citrate Salt is used as a skeletal muscle relaxant which exhibits antihistaminic properties.

 

Synonyms:

• Orphenadrine dihydrogen citrate; N,N-Dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine 2-hydroxypropane-1,2,3-tricarboxylic acid salt; N,N-dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanaminium 3,4-dicarboxy-3-hydroxybutanoate

ORPHENADRINE CITRATE JAI RADHE SALES

Product Details:

This compound inhibits proliferation and supresses gene expression in bladder smooth muscle cells.

 

Synonyms:

• Tropax; Cystrin; Dridase; Inobase; mj4309-1; ditropan; MJ 50-58; Pollakisu; Oxybutynin HC; Oxybutynin HCL

OXYBUTYNIN CHLORIDE JAIRADHESALES

Product Details:

Oxymetazoline Hydrochloride is a direct sympathomimetic agent. Is a nonselective adrenomimetic of α1A-AR and α 2A-AR (α1-AR and α2-AR adrenergic receptor) agonists. Since vascular beds widely express α1 receptors, the action of Oxymetazoline results in vasoconstriction due to its action on endothelial α2 receptors. Oxymetazoline Hydrochloride is an inhibitor of SR-2C and an activator of SR-1A, SR-1B, SR-1D and SR-2C.

Synonyms:

• Oxymetazoline HCl; Afrazine; 2-(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazol-3-ium

Product Details:

This drug has a specific local analgesic effect in the urinary tract, promptly relieving burning & pain and gives symptomatic relief of dysuria

Synonyms:

• nc150; pirid; URODINE; azodyne; dolonil; giracid; pyrizin; sedural; urazium; uriplex

PHENAZOPYRIDINE HCL JAIRADHE SALES

Product Details:

A white crystalline powder. A faint amine-like odor.Soluble in water and in alcohol.

Synonyms:

• pheniramine hydrogen maleate; N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine (2Z)-but-2-enedioate; 2-[3-(dimethylammonio)-1-phenylpropyl]pyridinium (2E)-but-2-enedioate; 2-[3-(dimethylammonio)-1-phenylpropyl]pyridinium propanedioate

Product Details:

A white or practically white, crystalline powder

Synonyms:

• Uri; fenox; emagrin; efricel; lexatol; rhinall; synasal; almefrin; consdrin; fenilfar

Product Details:

White powder, odourless; somewhat hygroscopic

Synonyms:

• solantoin; solantyl; solublephenytoin; tacosal;5,5-Diphenylhydatoin sodium salt; 5,5-Diphenyl-2,4; Phenytoinum Natricum; 2,4-Imidazolidinedione, 5,5-diphenyl-, monosodium salt

Product Details:

Yellowish-brown to reddish brown, amorphous powder, having a slight, characteristic odor. Its solution is acid to litmus

 

Synonyms:

• Betadine; Isodine;1-Vinyl-2-Pyrrolidinone Polymers Iodine Complex; Surgicide; Surgicide(R); Scrubidine; Scrubidine(R); Povidone Iodine

 

Application:

• PVP-I is a broad spectrum antiseptic for topical application. It is used in first aid for minor cuts, grazes, burns, abrasions and blisters. PVP-I has broad applications in medicine as a surgical scrub; for pre- and post-operative skin cleansing; for the treatment and prevention of infections in wounds, ulcers, cuts and burns; for the treatment of infections in decubitus ulcers and stasis ulcers; in gynecology for vaginitis associated with candidal, trichomonal or mixed infections.

Product Details:

The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.

Application:

• For the reduction of serum uric acid concentrations in chronic gouty arthritis and tophaceous gout in patients with frequent disabling gout attacks. Has also been effectively used to promote uric acid excretion in hyperuricemia secondary to the administration of thiazide and related diuretics.

Product Details:

White or almost white powder

 

Synonyms:

• Arial; SN 408; Siduomi; Serevent; GR 3343G; GR-33343G; Salmetedur;Serevent Diskus; GR 33343X XINAFOATE; SalMeterol Solution

Product Details:

Inhibits action of acetylcholine at post-ganglionic synapses; muscarinic acetylcholine receptor antagonist; antispasmodic; reduces gastric acid secretion.

Synonyms:

• (pantas; ercorax; kivatin; ketaman; sc-3171; ercotina;pervagal; propantel; Corrigast;i umbromide

 

IUPAC Name:

• N-isopropyl-N-methyl-N-{2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl}propan-2-aminium bromide

 

PROPANTHELINE BROMIDE JALRADHESALES

Product Details:

Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent children.

Synonyms:

• Sulfur Selenide; Selenium Disulfide; Seleniummonosulfide; Selenium(Ii)Sulphide; Selenium(Iv) Sulfide; Seleniummonosulphide; Selenium Sulfide (Ses)

Product Details:

Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase and bone resorption. Studies suggest that Pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-κB pathway activation, via the endothelial protein C receptor.

Synonyms:

• pamidronate disodium; disodium (3-amino-1-hydroxypropane-1,1-diyl)bis[hydrogen (phosphonate)] ;pamidronate disodium salt;3-amino-1-hydroxy-1-phosphonopropyl phosphonic acid disodium salt;phosphonate, P,P'-(3-amino-1-hydroxypropylidene)bis-, sodium salt (1:2);

PAMIDRONATESODIUM IAIRADHESALES

Product Details:

Sodium picosulfate converted by colonic bacteria to BHPM, which directly stimulates colonic peristalsis. Magnesium oxide and anhydrous citric acid combine to form magnesium citrate, an osmotic laxative that causes water retention within the GI tract.

Synonyms:

• LA 391; C13072; DA 1773; Evacuol; Picolax; DA-1773; Laxoberal;Picosulfate Sodium; sodium picosulfate; Bisacodyl IMpurity D

Product Details:

A white to off-white crystalline powder

Synonyms:

• Magnesium,bis[5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]-,[T-4-(S),(S)]-; (-)-Omeprazole magnesium; (S)-Omeprazole magnesium; H 199/18; Nexium; Perprazole; Raciper

 

IUPAC Name:

• Magnesium; 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide; 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide

 

Product Details:

Synonyms:

• sn307; Zudan; Zofran; EMeset; Zophren; Osetron; GR 38032F; NSC 665799; Ondansetron HCL; OdansetronHCldihydrate

Product Details:

A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated.

Synonyms:

• Pimozide; 1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinon; 1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinone; 1-(4,4-bis(p-fluorophenyl)butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine;mcn-jr-6238; orap; 1-[1-(4,4-Bis[4-Fluorophenyl]Butyl)-4-Piperidinyl]-1,3-Dihydro-2H-Benz-Imidazol-2-One;3-(1-(4,4-Bis(4-Fluorophenyl)Butyl)-4-Piperidyl)-1H-Benzimidazol-2-One

 

Application:

• Used for the suppression of motor and phonic tics in patients with Tourette''s Disorder who have failed to respond satisfactorily to standard treatment.

Product Details:

Ranitidine hydrochloride is a histamine H2-receptor antagonist used in the treatment of gastrointestinal lesions due to excessive gastric acid secretion.

Synonyms:

• Zantac; Ranitidine Hcl; Ranitidine (Ranitidine); Ranitidine Hydrochloride; Ranitidine Hydrochloride Bp93; [(Dimethylamino)Methyl]Furfuryl]Thio]Ethyl]-N''-Methyl-2-Nitrovinylidenediamine Monohydrochloride; N-[2-[5-[(Dimethylamino)Methyl]Furfurylthio]Ethyl]-N''-Methyl-2-Nitro-1,1-Ethenediamine Hydrochloride; N-[2-[[5-[(Dimethylamino)Methyl]Furfuryl]Thio]Ethyl]-N''-Methyl-2-Nitrovinylidenediamine Monohydrochloride; N-[2-[[[5-[(Dimethylamino)Methyl]-2-Furanyl]Methyl]Thio]Ethyl]-N''-Methyl-2-Nitro-1,1-Ethanediamine Hydrochloride;N-[2-[[[-5-[(Dimethylamino)Methyl]-2-Furanyl]Methyl]Thio]Ethyl]-N''-Methyl-2-Nitro-1,1 Ethenediamine, Hydrochloride

 

IUPAC Name:

• (E)-1-N-[2-[[5-(dimethylaminomethyl)furan-2-yl]methylsulfanyl]ethyl]-1-N''-methyl-2-nitroethene-1,1-diamine hydrochloride

 

RANITIDINE HCL JAIRADHE SALES

Product Details:

One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis

Synonyms:

• wr2978; bw50-63; Malacid; Malocid; nsc3061; RP 4753; WR 2978; 4753r.p.; BW 50-63; Daraclor

 

Application:

• For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

PYRIMETHAMINEPOWDER JAIRADHESALES

Product Details:

Rivastigmine hydrogen tartrate is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and Parkinson''s disease.

Synonyms:

• Exelon; Rivastigmine; Rivastigmine Tartrate

 

IUPAC Name:

• (2S,3S)-2,3-dihydroxybutanedioic acid; [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate