Active Pharmaceutical Ingredients 2

Product Details:

Dark brown to reddish brown homogenous powder, almost odorless, sweet in taste and hygroscopic.

Synonyms:

• Iron Sucrose; Saccharated iron oxide; Ferric hydroxide sucrose complex; Iron-sorbitol-citric acid complex.; iron(2+) (2R,3S,4S,5S)-2,3,4,5-tetrahydroxyhexanedioate (non-preferred name)

Product Details:

Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.

 

Synonyms:

• HIA; INH; INAH; fsr3; GINK; Cedin; FSR 3; fsr-3; Hyzyd; In-73

Product Details:

Levalbuterol Hydrochloride is a β2-adrenoceptor agonist.

 

IUPAC Name:

• 1,3-Benzenedimethanol,a1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-,hydrochloride, (R)-; 1,3-Benzenedimethanol, a1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-,hydrochloride, (a1R)-(9CI); (-)-Salbutamol hydrochloride; (R)-Salbutamol hydrochloride; Levalbuterolhydrochloride;Levosalbutamol hydrochloride; Xopenex

Product Details:

White to off white crystalline powder

 

IUPAC Name:

• [2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride

 

Product Details:

Lidocaine Base India is used topically to relieve itching, burning and pain of inflamed skin inhibit ion fluxes across membranes, particularly sodium transport across the cell membrane decreases increasing depolarization phase action potential blocking nerve action potential.

Synonyms:

• Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-; 2'',6''-Acetoxylidide, 2-(diethylamino)-; «alpha»-(Diethylamino)-2, 6-acetoxylidide; Anestacon; Duncaine; Gravocain; Isicaina;Isicaine; Leostesin; Lignocaine; Maricaine; Rucaina; Solcain; Xycaine; Xylestesin; Xylocain; Xylocaine; Xylocitin; Xylotox;2-(Diethylamino)-2'',6''-acetoxylidide; «alpha»-Diethylamino-2,6-dimethylacetanilide; «alpha»-Diethylaminoaceto-2,6-xylidide;«omeg

Product Details:

Lidocaine hydrochloride stops the feeling of pain. It can be used During medical procedures. Lidocaine hydrochloride Also can be used to treat Un certain types of irregular heartbeats.Lidocaine HCL used topically to relieve itching, burning and pain of inflamed skin inhibit ion fluxes across membranes, particularly sodium transport across the cell membrane, increase decreases depolarization phase action potential blocking nerve action potential;Indications: local dental anesthetic peripheral nerve blocks , caudal anesthesia , epidural spinal anesthesia, surgery.Treatment consists essentially maintaining the circulation and respiration and controlling seizures. The circulation can be maintained with plasma infusions or electrolyte solutions suitable . Seizures can be controlled by intravenous.

Synonyms:

• Dolicaine; Linocaine Hcl; Lidocaine Hcl Usp; Linocaine Hydrochlor; Lidocaine Hcl Hydrate; Linocaine Hydrochloride; LidocaineHclLidocaineHclBp; Linocaine hydrochloride hydrate; lidocainemonohydratehydrochloride; Lidocaine Hydrochloride BP98 USP24

Product Details:

L-Selenomethionine displays antioxidant activity and has been shown to increase the activity of glutathione peroxidase in endothelial cells. Glutathione peroxidase protects cells from oxidative damage, such as DNA strand breaks, mutations and interference with protein tyrosine-based signaling and other protein functions due to formation of 3-nitrotyrosine, caused by excessive peroxynitrite. L-Selenomethionine administration to cancer cell lines (MCF-7/S breast carcinoma, DU-145 prostate cancer cells and UACC-375 melanoma) results in apoptotic cell death and aberrant mitosis. These human tumor cell lines exhibited dose-dependent growth inhibition by L-Selenomethionine in the micromolar range (45 to 130 μM), while growth inhibition of normal fibroblasts required 1 mM L-Selenomethionine.

Synonyms:

• (S)-(+)-2-Amino-4-(Methylseleno)Butanoic Acid; (S)-2-Amino-4-(Methylseleno)Butyric Acid; Semet; Selenomethionine, L-(+)-;Seleno-L-Methionine; L-(+)-2-Amino-4-(Methylseleno)Butanoic Acid; L-(+)-Selenomethionine; L-Selenomethionine

 

Product Details:

Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.

Synonyms:

• (S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol; Levodropropizine; (2S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol; Danka; l-Dropropizine; Levotuss; LVDP; Rapitux

Product Details:

Levo Mepromazine Maleate is the (R) optical isomer of Methotrimeprazine.

 

Synonyms:

• Sofmin; Neruocil; Neuractil; Levohalte; Neurocil (tablet); Levomepromazine meleate; Levomepromazine maleate; RP 7044 hydrogen maleate; Levomepromazine, maleic acid; 2-Methoxytrimeprazine maleate

Product Details:

Losartan Potassium is a specific antagonist of the angiotensin II receptor subtype AT1. Antagonism of the AT1 receptor and interference of association between AT1 and angiotensin II produces vasodilation and reduction of hypertension. This antagonism has other downstream effects, including a correlated antagonism of the thromboxane A2 receptor, inhibition of platelet aggregation, and induction of peroxisome proliferator-actived receptor gamma (PPARγ) activity.

Synonyms:

• potassium[2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol

 

IUPAC Name:

• [2-butyl-4-chloro-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazol-5-yl]methanol

Product Details:

Gabapentin enacarbil is marketed under the name Horizant®. It is a prodrug of gabapentin, and indicated in adults for the treatment of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).

Synonyms:

• Forgabapentine; Gabapentin-Lactam; Gabapentin Usp Rc A; 3-Azaspiro[4.5]Decan-2-One; 2-Aza-Spiro[4.5]Decan-3-One;3-Azaspiro-[4,5]Decan-3-One; Pentamethylene Pyrrolidinone; Gabapentin Related Compound A; 3,3-Pentamethylene-4-Butyrolac; 3,3-Pentenylene-4-Butyrolactam

Product Details:

Glyburide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. Glyburide has been shown to decrease fasting plasma glucose, postprandial blood glucose and glycosolated hemoglobin (HbA1c) levels (reflective of the last 8-10 weeks of glucose control). Glyburide appears to be completely metabolized, likely in the liver. Although its metabolites exert a small hypoglycemic effect, their contribution to glyburide’s hypoglycemic effect is thought to be clinically unimportant. Glyburide metabolites are excreted in urine and feces in approximately equal proportions. The half-life of glyburide appears to be unaffected in those with a creatinine clearance of greater than 29 ml/min/1.73m2

Synonyms:

• 5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide; N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N′-cyclohexylurea

Product Details:

Glimepiride is the first III generation sulphonyl urea it is a very potent sulphonyl urea with long duration of action.

Synonyms:

• Amary; Amaryl; Hoe490; Glimepirid; Glimpiride; Grimepride; Glimperide; Glimipride; Glimepiride; Climepiride

Product Details:

Glycopyrrolate is a synthetic anticholinergic agent with a quaternary ammonium structure. A muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics.

Synonyms:

• ahr504; tarodyl; robanul; asecryl; tarodyn; nodapton; gastrodyn; NSC 250836; NSC 251251

 

Application:

• For use as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions, to reduce the volume and free acidity of gastric secretions and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation.

Product Details:

An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Synonyms:

• 2-G; 2/G; g87; gge; G 87; Dilyn; Gvaja; my301; Resil;Resyl

Product Details:

A white or almost white powder

Synonyms:

• Haloperidol decanoate [USAN:BAN:JAN]; Decanoic acid, 4-(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl ester; Decanoic acid, ester with 4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4''-fluorobutyrophenone; Depot haloperidol; Haldol decanoas; Haldol decanoate; Halomonth; Haloperidol depot; KD 136; KD 16; KD-136; Neoperidole; R 13,672; R 13672; UNII-AC20PJ4101; 4-(4-Chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidyl decanoate; 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl decanoate

Product Details:

A white to off white, odourless crystalline powder

Synonyms:

• Mono-Hydrazinophthalazine Hcl; Hydralazine Hydrochloride; 1-Phthalazinylhydrazine Hydrochloride; 1-Hydrazinophthalazine Hydrochloride; 1(2H)-Phthalazinone, Hydrazone, Monohydrochloride;1-Hydrazinophthalazinemonohydrochloride; 1-Hydrazino-Phthalazinmonohydrochloride; Aiselazine

Product Details:

Hydroxychloroquine is classified as an anti-malarial medication, and is one of a number of drugs which have been used for many years in the treatment of malaria. It is useful in treating systemic lupus erythematosus as well as rheumatoid arthritis and Sjogren's Syndrome.

Synonyms:

• 7-Chloro-4-[4-[ethyl-(2-hydroxyethyl)amino]-1-methylbutylamino]quinoline Hydroxychloroquine sulfate,  7-Chloro-4-[4-[ethyl-(2-hydroxyethyl)amino]-1-methylbutylamino]quinoline,

Product Details:

Inhibits bone resorption as a sodium salt and complexed with technetium Tc 99m for bone imaging. The monophosphonates are not active and the biphosphonates are used in disorders affecting the skeleton such as metastatic disease, asteoporosis and Paget's.

Synonyms:

• Bondronat; Ibandronate sodium; Ibandronate sodiuM Bondronat; Ibandronate Sodium Anhydrous; (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt; Bondronat, (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium;sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid

Product Details:

Imipramine Hydrochloride is a tricyclic antidepressant. Inhibits the serotonin and norepinephrine transporters but has little effect on the dopamine transporter.

Synonyms:

• g22355; imidol; ia- pram; imavate; iprogen; efuranol;d ynazina; deprinol; fujisawa; janimine

Product Details:

This compound belongs to the hydroxyquinolines. These are compounds containing a quinoline moiety bearing an hydroxyl group.

 

Synonyms:

• 5-Chloro-7-iodo-8-hydroxyquinoline; Clioquinol; 5-Chloro-7-iodoquinolin-8-ol; Iodochlorohydroxyquin; Iodochlorohydroxyquinoline

Product Details:

Iodoform is used in wide range of medicals industrial applocations as well as in human and animal nutrition products such as antiseptics and disinfectants, pharmaceutical intermediates, polarizing films for liquid crystal display [LCD] chemicals. Iodine derivatives are also used as organic building blocks, analytical reagents etc.

Synonyms:

• CHI3; ioforme; Iodofrm; Jodoform; IODOFORM; iodoforme;d ezinfektv; NCI-C04568; IodoforM NF;Trijodmethan

Product Details:

Iron III Hydroxy Polymaltose Complex Product Enquiry

 

 

Deep brown coloured free flowing powder

 

IUPAC Name:

• 2-[2-[bis(2-oxido-2-oxoethyl)amino]ethyl-(carboxymethyl)amino]acetate; iron(3+)oethyl)amino]acetate; iron(3+)

Product Details:

One of the triazole antifungal agents that inhibits cytochrome P-450-dependent enzymes resulting in impairment of ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis & aspergillosis.

Synonyms:

• R51211; Orungal; Sempera; Sporanox; Itrizole; Canditral; Sporamelt; Triasporin; Akos 92112; Oricomzole

 

Application:

• For the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients: pulmonary and extrapulmonary blastomycosis, histoplasmosis, aspergillosis, and onychomycosis.

 

IUPAC Name:

• (2R,4S)-rel-1-(Butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one

Product Details:

White to off-white, crystalline powder

Synonyms:

• (+/-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris(hydroxymethyl)methylamine salt; Toradol; Ketorolac tris salt; 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid-2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)

Product Details:

L-Glutamic acid gamma-(7-amido-4-methylcoumarin) is a substrate for aminopeptidase a or the assay of gamma-glutamyl transferase producing a blue fluorescent solution upon cleavage.

 

Synonyms:

• Glu; L-Glu; Aciglut; Glusate; H-Glu-Oh; Glutacid; glutamic; Glutaton; FEMA 3285; H-L-GLU-OH

Product Details:

L-lysine is classified as an essential amino acid for humans and must be supplied in the diet. The male adult’s daily requirement is 12 mg per kg of body weight. It is extremely rare for a diet to contain insufficient quantities of lysine. Vegetarians who follow a macrobiotic diet and athletes who exercise vigorously on a frequent basis must take care to obtain sufficient L-lysine. Beans, peas and lentils are the best source of lysine.

Synonyms:

• L-Gen; darvyl; Lysion; lyamine; LYS, HCL; NSC 9253; L-LYS HCL; LYSINE HCL; Lysine (K); L-LYSINE HCL

Product Details:

Lansoprazole is a proton pump inhibitor which prevents the stomach from producing acid. It is manufactured by TAP Pharmaceutical Products. Lansoprazole has been marketed for many years and is one of several PPI's available.

Synonyms:

• 2-[[[3-Methyl-1-oxido-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole

Applications:

• For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.

Product Details:

Loratadine is a non antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells. Loratadine is a selective inverse peripheral histamine H1-receptor agonist (IC50 > 32 μM).

Synonyms:

• Lisino; Tadine; Civeran; Loranox; Claritin; Clarityn; Claratyne; SCH-29851; Claritine;Loratadine

 

IUPAC Name:

• Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate

Product Details:

Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug.

Synonyms:

• LORNOXICAM; AKOS 93662; 6-CHLORO-4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE; 2h-thieno(2,3-e)-1,2-thiazine-3-carboxamide,6-chloro-4-hydroxy-2-methyl-n-2-py; chlortenoxicam;ridinyl-,1,1-dioxide; 6-Chloro-4-hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide-1,1-dioxide; Lornoxicam Consulted Standard

Application:

• For the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.

 

IUPAC Name:

• (3E)-6-chloro-3-[hydroxy(pyridin-2-ylamino)methylene]-2-methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]thiazin-4-one 1,1-dioxide

 

 

Product Details:

For management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia. For primary prevention of coronary heart disease and to slow progression of coronary atherosclerosis in patients with coronary heart disease.

IUPAC Name:

• (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate

Product Details:

A white or almost white crystalline powder, hygroscopic

 

Synonyms:

• Sodium valproate, Valproate sodium, Depakene, Epilim, Convulex, Eurekene, Labazene, Orfiril, Valerin, Natrium valproat, Selenica, Sodium 2-propylpentanoate, Valproic acid sodium salt, Dipropylacetate sodium, Sodium dipropylacetate, Depakene (TN), Selenica (TN), Sodium bispropylacetate, Valproic acid sodium, Valproinsaeure, natrium

Product Details:

Used in surgical procedures where a rapid onset and brief duration of muscle relaxation is needed (includes intubation, endoscopies, and ECT) This compound belongs to the cholines. These are organic compounds containing a N,N,N-trimethylethanolammonium cation.

Synonyms:

• Skolin; Ditilin; Midarine; Pantolax; Anectine; Lysthenon; Lysthenone; Myoplegine; Succicuran; Succinyl-Asta

Product Details:

Racecadotril is a potent CD10 (enkephalinase) inhibitor which exhibits selective antisecretory activity.

Synonyms:

• Redotil; tiorfan; Acetorphan; Racecadotril; Racecadortril; Racecadotril: Acetorphan; Benzyl 2-(3-(acetylthio)-2-benzylpropanaMido)acetate; n-(2-((acetylthio)methyl)-1-oxo-3-phenylpropyl)-glycinphenylmethylester; n-[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]-glycine phenylmethyl ester; (+-)-n-(2-((acetylthio)methyl)-1-oxo-3-phenylpropyl) glycinephenylmethyleste

Product Details:

Irbesartan is an angiotensin receptor blocker (ARB) used mainly for the treatment of hypertension. It competes with angiotensin II for binding at the AT1 receptor subtype. Unlike ACE inhibitors, ARBs do not have the adverse effect of dry cough. The use of ARBs is pending revision due to findings from several clinical trials suggesting that this class of drugs may be associated with a small increased risk of cancer.

Synonyms:

• 2-Butyl-3-[[2''-(1H-tetrazol-5-yl)[1,1''-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one-d3

 

Application:

• For the treatment of hypertension, as well as diabetic nephropathy with an elevated serum creatinine and proteinuria (>300 mg/day) in patients with type 2 diabetes and hypertension. Irbesartan is also used as a second line agent in the treatment of congestive heart failure.

Product Details:

Yellow to yellow-greenish coloured powder

 

Synonyms:

• Ferricholinatum, Ferrocholinate, Iron choline citrate, Ferrocholinate citrate, Ferric choline citrate, Ferrocholinate [INN], Iron choline citrate complex, Iron-choline citrate complex, Ferrocholinatum [INN-Latin], Ferrocolinato [INN-Spanish], EINECS 215-649-7, Iron 2-hydroxy-1,2,3-propanetricarboxylate complex, 2-Hydroxy-1,2,3-propanetricarboxylic acid, iron complex, ETHANAMINIUM, 2-Hydroxy-N,N,N-Trimethyl-, Hydroxy(2-Hydroxy-1,2,3-Propanetricarb, 1336-80-7, 2-Hydroxy-N,N,N-trimethylethanaminium triaqua(2-hydroxy-1,2,3-tricarboxylatoferrate, (OC-6-44), Chelate prepared by reacting equimolar quantities of freshly precipitated ferric hydroxide with choline dihydrogen citrate, Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, (OC-6-44)-triaqua(2-hydroxy-1,2,3-propanetricarboxylato(4-))ferrate(1-), Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxy(2-hydroxy-1,2,3-propanetricarboxylato(4-))ferrate(1-), Ferrate(1-), triaqua(2-hydroxy-1,2,3-propanetricarboxylato(4-))-, (oc-6-44)-, 2-hydroxy-N,N,N-trimethylethanaminium

 

Application:

• used in chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.

Product Details:

For symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moderate pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.

Synonyms:

• aneol; Dexal; Iso-K; Topre; ORUDIS; Epatec; Fastum; Lertus; ru4733; Toprec

 

Application:

• Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.