Active Pharmaceutical Ingredients-API

Product Details:

Bupropion hydrochloride (HCL) is an antidepressant used for smoking cessation and to treat a variety of conditions, including depression and other mental/mood disorders. Antidepressants can help prevent suicidal thoughts/attempts and provide other important benefits.

Product Details:

Plasticizer for cellulose esters and ethers, preservative for biological fluids, hypodermic soln and soln of alkaloids. Pharmaceutical aid (antimicrobial).

Synonyms:

• 2-Trichloromethyl-2-propanol;Chlorbutol; 2-Trichhloromethyl-2-propanol; 2-Methyl-1,1,1-trichloro-2-propanol; Acetone chloroform; Chloretone; 1-Methyl-1-(trichloromethyl)ethanol; 1,1,1-Trichloro-2-methyl-2-propanol; 1,1,1-trichloro-2-methylpropan-2-ol; Trichloro-tert-buty alcohol;

Product Details:

Dicyclomine is used to treat the symptoms of irritable bowel syndrome. Dicyclomine is in a class of medications called anticholinergics. It relieves muscle spasms in the gastrointestinal tract by blocking the activity of a certain natural substance in the body.

Synonyms:

• Atumin; dyspas;Bentyl); mamiesan; oxityl-p; bentomine; merbentyl; Magesan P; procyclomin; di-syntramine

Product Details:

Dexamethasone Sodium Phosphate is a systemic corticosteroid. Dexamethasone Sodium Phosphate induces apoptosis and inhibits sodium phosphate symporter. Dexamethasone Sodium Phosphate is also used in the treatment of emetic effects of cancer therapy and epicondylitis. Dexamethasone Sodium Phosphate is an activator of GR.

Synonyms:

• Dexamethasone Phosphate Sodium; dexamethasone 21-(disodium phosphate); Dexamethasone Sodium Phosphate; disodium (11beta,16alpha)-9-fluoro-11, 17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate; (9R,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;Dexamethasone Phosphate Disodium.

Product Details:

Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an ischemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.

Synonyms:

• alunex; piriex; Haynon;c-meton; ibioton; lorphen; piriton; teldrin; Puermin; allergin

Product Details:

This compound belongs to the hydroxyquinolines. These are compounds containing a quinoline moiety bearing an hydroxyl group.

Synonyms:

• Amebil; Bactol; corque; cortin; hysone; Amoenol; Emaform; Nioform; oralcer; Rometin

Product Details:

Light yellowish to tan, microcrystalline Powder: odourless

Synonyms:

• ss578; Dyodin; oquin; SS 578; Yodoxin; Zoaquin; EMBEQUIN; Disoquin; Sebaquin; NSC 8704

Product Details:

Cholestyramine resin, Agn-pc-0j29wj, Chembl2104535, [4-[3-(4-ethylphenyl)butyl]phenyl]-trimethylazanium;chloride

Product Details:

Benzethonium is a medication used as to clean hands and clean minor cuts and scrapes. Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.

Product Details:

The product is a white or kind of white tablets;For all the pain,for short-term elimination of trauma and postoperative pain, swelling, severe pain and pain caused by various reasons;Tablet or injection can be used to relieve moderate to severe postoperative pain, including the abdomen, chest, gynecological, dental, orthopedic and urologic surgery.

Synonyms:

• L-Ketoprofen trometamol; dexketoprofen trometamol; (s)-ketoprofen trometamol; Dexketoprofen TroMetaMol API; 2-amino-2-(hydroxymethyl)-1,3-propanediol (s)-3-benzoyl-alpha-methylbenzeneacetate

Product Details:

It is used to treat conditions such as arthritis, blood problems, immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It decreases your immune system's response to various diseases to reduce symptoms such as pain, swelling and allergic-type reactions.

Product Details:

Chloroquine Phosphate is an antimalarial agent that has been discovered to have a distinct affinity for melanin. Used in the treatment of arthritis, malaria and Lupus. Chloroquine Phosphate is a substrate of MRP.

Synonyms:

• 7-chlor-4-(4-(diaethylamino)-1-methylbutylamino)-chinolindiphosphat; 7-chloro-4-((4’-diethylamino-1-methylbutyl)amino) quinolinediphosphate; 7-chloro-4-(4-diethylamino-1-methyl-butylamino)-quinolindiphosphate; alermine; aralendiphosphate; chingaminphosphate; chloroquindiphosphate; chloroquinebis(phosphate)

prednisolone sodium phosphate

CAS # 125-02-0

Phortisolone

Disodium prednisolone 21-phosphate

Prednisolone phosphate sodium

Product Details:

Synonyms:

• Chloropropamide; Chlorpropamide; 1-(4-Chlorophenylsulfonyl)-3-Propylurea; 1-[P-Chlorobenzenesulfonyl]-3-Propylurea; 1-((P-Chloropenyl)Sulfonyl)-3-Propyl-Ure; 1-((P-Chlorophenyl)Sulfonyl)-3-Propyl-Ure; 1-(P-Chlorophenylsulfonyl)-3-Propylurea; 1-Chloro-4-(([(Propylamino)Carbonyl]Amino)Sulfonyl)Benzene

Product Details:

Cinnarizine is an anti-histaminic drug which is mainly used for the control of vomiting due to motion sickness. Cinnarizine was first synthesized by Janssen Pharmaceutica in 1955. It acts by interfering with the signal transmission between vestibular apparatus of the inner ear and the vomiting centre of the hypothalamus. The disparity of signal processing between inner ear motion receptors and the visual senses is abolished, so that the confusion of brain whether the individual is moving or standing is reduced. Vomiting in motion sickness is actually a physiological compensatory mechanism of the brain to keep the individual from moving so that it can adjust to the signal perception. Cinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which happen mostly in brain. It is also effectively combined with other nootropics, primarily piracetam; in such combination each drug potentiate the other in boosting brain oxygen supply.

Synonyms:

• 1-benzhydryl-4-trans-cinnamylpiperazine; Cinnarazine; 1-(diphenylmethyl)-4-[(1E)-3-phenylprop-1-en-1-yl]; Stugeron

 

Application:

• For the treatment of vertigo/meniere''s disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.

 

Product Details:

Chlorzoxazone, a synthetic compound, inhibits antigen-induced bronchospasms and, hence, is used to treat asthma and allergic rhinitis. Chlorzoxazone is used as an ophthalmic solution to treat conjunctivitis and is taken orally to treat systemic mastocytosis and ulcerative colitis. Chlorzoxazone is also a centrally-acting agent for painful musculoskeletal conditions. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic reflex a.c. involved in producing and maintaining skeletal muscle spasm of varied etiology. The clinical result is a reduction of the skeletal muscle spasm with relief of pain and increased mobility of the involved muscles.

Synonyms:

• Mioran; Miotran;Neoflex; Solaxin; Escoflex; Paraflex; Biomioran; Myoflexin; usafma-10; Myoflexine

 

Application:

• For the relief of discomfort associated with acute painful musculoskeletal conditions.

Product Details:

Citalopram hydrobromide is a salt form of Citalopram (sc-201123). Citalopram is a selective inhibitor of ST (5-hydroxytryptamine/serotonin transporter) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies in indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavior.

Synonyms:

• Erdostein; Citalopram Hbr; Citalopram-D4Br; Citalopram Hbr Api; Citalopramehydrobromide; Citalopram Hydrobromide; Citalopram Bromohydrate; Citaloplam Hydrobromide; Citalopram Hydrobromide, Usp;(+/-)-Citalopram Hydrobromide

Product Details:

Clenbuterol Hydrochloride acts as a β2-adrenoreceptor aganist.

Synonyms:

• nab365; Alvaprol; spiropent; NAB 365CL; Ventipulmi; ventipulmin; CLENBUTEROL HCL; planiparthydrochloride; clenbuterolclorhidrato; Clenbuterol in Methanol

Product Details:

Clidinium Bromide is used as an antiplasmodic and is an anticholinergic.

Synonyms:

• Clidinium Bromide; 3-[(Hydroxyphenylacetyl)Oxy]-1-Methyl-1-Azoniabicyclo[2,2,2]Octane Bromide; 3-Hydroxy-1-Methylquinuclidinium Bromide Benzilate; Quarzan; Ro-2-3773; 1-Methyl-3-Benzil-Oxyloxy-Quinuclidiniumbromide; 3-((Hydroxydiphenylacetyl)Oxy)-1-Methyl-1-Azoniabicyclo(2.2.2)Octanbromi; 3-(2,2-Diphenyl-2-Hydroxyethanoyloxy)-Quinuclidiniumbromide

Product Details:

White to off white crystalline powder

Synonyms:

• clopidogrel hydrogen sulphate; clopidogrel sulphate; clopidogrel bisulfate; methyl (+)-(s)-a-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4h)acetate, hydrogen sulfate salt; (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid sulfate (1:1); (+/-)-Clopidogrel bisulfate; Clopidogerl Bisulfate; Clopidogrel bisulphate Ⅰ/Ⅱ; Clopidogrel Bisulfate II; Clopidogrel Bisulfate I; Clopidogrel Bisulfate, FormI/FormII; Clopidogrel sulfate; Clopidogrel Hydrogensulfate

Product Details:

Cromolyn disodium salt blocks the release of pro-inflammatory mediators, such as histamine, from mast cells.

Synonyms:

• Cromoglycate; Cromoglycic acid

Product Details:

Cyclopentolate Hydrochloride is a cholinergic aromatic amine.

Synonyms:

• Alnide; Cyclogyl; Zyklolat; Mydplegic; Ak-Pentolate; Labotest-Bb Lt00244824; Cyclogyl Hydrochloride; Cyclopentolate Hcl Usp; Cyclopentolate Hydrochloride; Cyclopentolatehydrochloride,Usp

Product Details:

Cyproheptadine hydrochloride is a migraine prophylactic and Non-selective SR-2A (5HT2) antagonist. Cyproheptadine hydrochloride is an inhibitor of Histamine H1 Receptor and SR-2C.

Synonyms:

• Cyproheptadine Hcl; Cyproheptadinehcluspgrade; Cyproheptadine Hydrocloride; Cyproheptadine Hydrochlorid; Cyproheptadine Hydrochloride; Cyproheptadinehydrochloride, Usp; Cyproheptadine Hcl Usp(Crm Standard); Cyproheptadine Hydrochloride Hydrate; Cyproheptadine Hydrochloride (500 Mg);Cyproheptadine Hydrochloride [Usan:Jan]

Product Details:

Daunorubicin hydrochloride is a DNA intercalating anthracylcine natural product isolated from Streptomyces peucetius. Upon intercalation, Daunorubicin forms stable complexes with the DNA backbone, inhibiting normal functioning of the double helix and the proteins that interact with it. Daunorubicin is nearly identical in structure to Doxorubicin (sc-200923), with Doxorubicin containing a pendant hydroxyl group on the exocyclic ketone. The action of Daunorubicin has been correlated to efficacy in suppressing the proliferation of certain acute leukemias. Daunorubicin hydrochloride is an inhibitor of Topo I and Topo II and an activator of LASS.

Synonyms:

• Ondena; Cerubidine; Ndc0082-4155; Daunoblastin; Daunoblastina; Daunoblastine; Daunomycin Hcl; Daunomycine Hcl; Daunorubicin Hcl; Wp900 Hydrochloride

Product Details:

Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.

Synonyms:

• Allex; Aerius; Azomyr; Opulis; Clarinex; Sch-34117; Akos 92131; Nsc 675447; Neoclarityn; Desloratidine

 

Application:

• For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria.

Product Details:

Dexchlorpheniramine maleate is an antihistamine with anticholinergic (drying) and side effects. Antihistamines appear to compete with histamine for cell receptor sites on effector cells.

Synonyms:

• (+)-Chlorpheniramine Maleate Salt; Dexchloropheniramine Maleate; Dexchlorpheniramine Maleate; D-Chlorpheniramine Maleate; Gamma-[4-Chlorophenyl]-N,N-Dimethyl-2-Pyridinepropanamine Maleate Salt; (+)-2-(P-Chloro-Alpha-(2-(Dimethylamino)Ethyl) Benzyl)Pyridinemaleate; (S)-(+)-Chlorpheniraminemaleate; Dextrochlorpheniraminemaleate

Product Details:

Dextromethorphan Hydrobromide is a low affinity NMDA receptor antagonist. It is the d-form.

Synonyms:

• Delsym; Sisaal; Dextro; ROMILAR; medicon; tusilan; Tussade; antussan; metrorat; Dormetan

Product Details:

Dibucaine Hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. Target: Sodium Channel Dibucaine is an amide local anesthetic. Dibucaine reduced the degradation of BSA-gold complex in the reservosomes, which was not caused either by an inhibition of the whole proteolytic activity of the parasite or by a reduction on the expression levels of cruzipain.

Synonyms:

• 2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide Hydrochloride; 2-Butoxy-N-(2-diethylaminoethyl)cinchoninamide Hydrochloride; Benzolin; Cincaine; Cincaine Chloride; Nupercaine Hydrochloride; Percain; Percaine; Percamin S; Sovcain; Sovcaine

Product Details:

Dimenhydrinate (Dramamine, Gravol and Vertirosan) is an over-the-counter drug used to prevent motion sickness. It is closely related to diphenhydramine HCl, or Benadryl. It is primarily a H1-antagonist, but also possesses an antimuscarinic effect.

Synonyms:

• Diphenhydramine 8-chlorotheophyllinate; 2-(diphenylmethoxy)-N, N-dimethylethanaminium 8-chloro-1, 3-dimethyl-2-oxo-2, 3-dihydro-1H-purin-6-olate

Product Details:

White, odorless, crystalline powder

Synonyms:

• Benzhydramine hydrochloride; Dimedrolum; Benzhydramine; Diphenhydramine HCl; Diphenhydramine hydrochlorids; N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride; 2-(diphenylmethoxy)-N, N-dimethylethanamine; 2-(diphenylmethoxy)-N, N-dimethylethanamine hydrochloride (1:1)

Product Details:

For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.

Synonyms:

• 2,2,2,2-(4,8-dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilotetraethanol; Dipyridamole (FDA); 1,1'',1'',1''-{[4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo}tetraethanol; Dypyridamole

Product Details:

White to almost white powder.

Synonyms:

• Epival; Divalproex Sodium; Sodium Divalproate; Semisodiumvalproate; Valproate Semisodium; Divalproex Sodium (200 Mg); Sodium Hydrogen Divalproate; Valproic Acid Semisodium Salt; Dipropylacetic Acid Hemisodium Salt; Sodium Hydrogen Bis(2-Propylvalerate)

Product Details:

It is a amoebicide used in the treatment of intestinal Amebiasis, in chronic and acute amoebic dysentery.It is also used as an antiprotozoal.The drug is given after any tissue amoebicide to eradicate cysts.

Synonyms:

• 8073cb; furamide; amebiazol; furentomin; histomibal; diclofurazol; dichlofurazol; entamidefuroate; diloxanidfuroate; entamide2-furoate

Product Details:

Dimenhydrinate (Dramamine, Gravol and Vertirosan) is an over-the-counter drug used to prevent motion sickness. It is closely related to diphenhydramine HCl, or Benadryl. It is primarily a H1-antagonist, but also possesses an antimuscarinic effect.

Synonyms:

• Diphenhydramine 8-chlorotheophyllinate; 2-(diphenylmethoxy)-N, N-dimethylethanaminium 8-chloro-1, 3-dimethyl-2-oxo-2, 3-dihydro-1H-purin-6-olate

 

IUPAC Name:

• 8-chloro-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-ide; [2-(diphenylmethoxy)ethyl]dimethylazanium

 

Product Details:

A benzenesulfonamide-phthalimidine that tautomerizes to a benzophenones form. It is considered a thiazide-like diuretic.

Synonyms:

• Chlortalidone; 3-(4-chloro-3-sulphamoylphenyl)-3-hydroxyisoindolin-1-one; 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulfonamide

Product Details:

Clomiphene Citrate is a selective estrogen receptor modulator, which acts by inhibiting the action of estrogen on the pituitary. Clomiphene Citrate is an activator of PKC.

Synonyms:

• 1 - [P-(B-diethylaminoethoxy) phenyl] -1, 2-diphenylchlroethylene

Product Details:

Coenzyme Q10 is an electron transport chain component of the mitochondria, which assists proton and electron transfer across the inner mitochondrial membrane. Studies indicate that Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS3 (endothelial nitric oxide synthase, eNOS) and up-regulation of NOS2 (inducible nitric oxide synthase, iNOS). As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

Synonyms:

• CoQ10; Ubidecarenone; Ubiquinone-10; Q-10

Product Details:

Diacerein is also known as Diacetylrhein. Diacerein is used for treatment of Osteoarthritis. It works by inhibiting the synthesis of Interlukin-1, the main cytokine involved in cartilage destruction and enhances the synthesis of Proteoglycans & Hyluronic Acid which are the principal components of cartilage.

Synonyms:

• Diacerhein; 4,5-Bis(acetyloxy)-9,10-dioxo-2-anthracenecarboxylic acid; 4,5-bis(acetyloxy)-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid; 1,8-Diacetoxy-3-carboxyanthraquinone

Product Details:

This compound belongs to the organic thiocarbonic acid derivatives. These are organic compounds containing the thiocarbonic acid structure or a derivative thereof.

Synonyms:

• Ttd; Tts; DSF; Hoca; TATD; TETD; DRAM; TTS x; NOXAL; Nocbin

Product Details:

Dobutamine is a synthetic, direct acting catecholamine that is a ß1 receptor agonist. Dobutamine (HCl) is available as racemic mixture. Chemically it resembles dopamine. It provides additional pumping strength by stimulating the heart muscle and effective to treat low output acute heart failure.

Synonyms:

• 46236; Dobux; Dopmin; Inotrex;Dobutrex; NSC 299583; DOBUTAMINE HCL; Dobutamine hydrochloride; DL-Dobutamine hydrochloride; rac Dobutamine Hydrochloride