Active Pharmaceutical Ingredients 5

Product Details:

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.

Synonyms:

• Tu-199; Pritor; Bibr 277; Micardis; Telmisaran; Timishatan; Bibr 277Se; 21829-25-4; Telmisartan; Timetazidine

 

Application:

• Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).

 

IUPAC Name:

• 2-(4-{[4-Methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid

 

TELMISARTANPOWDER JAIRADHESALES

Product Details:

Timolol Maleate is a adrenergic receptor antagonist selective for β1-AR. Adrenergic receptors, or adrenoreceptors, are G-protein coupled receptors involved in a variety of sympathetic nervous system processes. Antagonists such as Timolol Maleate that affect the β adrenoreceptors are commonly known as beta blockers that decrease cardiac output.

Synonyms:

• S-(-)-1-(t-Butylamino)-3-[(4-morpholino- 1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate salt

 

IUPAC Name:

• (Z)-but-2-enedioic acid;(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

TIMOLOLMALEATE JAIRADHE SALES

Product Details:

A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.

 

Synonyms:

• Pleti; pletil; cp12574; bioshik; fasigyn; fasigin; tricolam; simplotan; sorquetan; tinidazol

 

Application:

• For the treatment of trichomoniasis caused by T. vaginalis in both female and male patients. Also for the treatment of giardiasis caused by G. duodenalis in both adults and pediatric patients older than three years of age and for the treatment of intestinal amebiasis and amebic liver abscess caused by E. histolytica in both adults and pediatric patients older than three years of age.

Product Details:

Tizanidine HCl is a skeletal muscle relaxant and centrally acting α2-AR (α2-adrenergic) agonist. Displays affinity for the I1-imidazoline receptor and exhibits spasmolytic activity.

 

Synonyms:

• Ab-021; Gibonz; Zanpeak; Ternelin; Sirdalud; Zanaflex; Enchinin; Astonelin; Ds-103-282;T Izanidine HCL

TIZANIDINE HCL JAIRADHE SALES

Product Details:

Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete’s foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.

Synonyms:

• 2-Naphthyl N-Methyl-N-(3-Tolyl)Thionocarbamate;Methyl 3-Tolylthiocarbamic Acid O-Naphthalen-2-Yl Ester;Methyl-[3-Methylphenyl]-Carbamothioic Acid O-2-Naphthyl Ester;Tolnafrate;Tolnaftate;Aftate;Carbamothioic Acid, Methyl(3-Methylphenyl)-, O-2-Naphthalenyl Ester;Carbanilic Acid, M,N-Dimethylthio-, O-2-Naphthyl Ester

Application:

• Tolnaftate topical is used to treat skin infections such as athlete's foot, jock itch, and ringworm infections. Tolnaftate is also used, along with other antifungals, to treat infections of the nails, scalp, palms, and soles of the feet. The powder and powder aerosol may be used to prevent athlete's foot.

Additional Information:

• Production Capacity: 1000

Product Details:

This compound belongs to the dioxolopyrans. These are compounds containing a dioxolopyran moiety, which consistts of a dioxole ring fused to a pyran ring.

Synonyms:

• Topina; Topamax; Topimax; EpitoMa; TopaMac; TopoMax; MCN 4853; EpitoMax; RWJ 17021; Topiramate

 

Application:

• Used for the treatment and control of partial seizures and severe tonic-clonic (grand mal) seizures and also for the prevention of migraine headaches. In children it is also used for treatment of Lennox-Gastaut syndrome. Indicated for the treatment and management of obesity.

TOPIRAMATEPOWDER JAIRADHESALES

Product Details:

A white to off white powder, odorless

 

Synonyms:

• Tremin; win511; peragit; pipanol; Broflex; Sedrina; Trihexy; paralest; pacitane; cyclodol

Product Details:

This compound belongs to the phenylpropylamines. These are compounds containing a phenylpropylamine moiety, which consists of a phenyl group substituted at the third carbon by an propan-1-amine.

Synonyms:

• mydrum; mydrin;mydriat; ro1-7683; Mydrapid; ydriacyl; Epitromin; epitromina; Tropicamid;ropicamide

 

Application:

• Indicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye.

TROPICAMIDE JAI RADHE SALES

Product Details:

This compound belongs to the gluco/mineralocorticoids, progestogins and derivatives. These are steroids whose structure is based on an hydroxylated prostane moiety.

Synonyms:

• Olux; Psorex; Clobex; Olux-E; cgp9555; GR-2/92; Karison;clobesol; Temovate; CCl 4725

 

Application:

• For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.

 

Product Details:

Diacerin is also known as Diacetylrhein. Diacerein is used for treatment of Osteoarthritis. It works by inhibiting the synthesis of Interlukin-1, the main cytokine involved in cartilage destruction and enhances the synthesis of Proteoglycans & Hyluronic Acid which are the principal components of cartilage.

Product Details:

Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. In humans, carbonic anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II). Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure. Brinzolamide is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Product Details:

Erythromycin Estolate belongs to macrolide antibiotics. It is the dodecyl sulfate(slat) of erythromycin 2''-propionate. It is mainly used in the treatment of the infections of staphylococcus resistant to penicillin and also used in the patients with the infections of streptococcus and pneumococcus and diphtheria bacilli carrier.

Synonyms:

• Erythromycin 2''-propionate dodecyl sulfate

 

IUPAC Name:

• [[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyloxan-3-yl] propanoate;dodecyl hydrogen sulfate

Product Details:

Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder.

Additional Information:

• Production Capacity: 5000kg
• Delivery Time: Immediate
• Packaging Details: 25 KG Hdpe Drum

Product Details:

A centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.

Application:

• For use as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions.

Product Details:

Piroxicam is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Piroxicam is in a class of medications called NSAIDs

Product Details:

Piroctone olamine (INN; also known as piroctone ethanolamine;) is a compound sometimes used in the treatment of fungal infections.^[1] Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone.

It is often used in anti-dandruff shampoo as a replacement for the commonly used compound zinc pyrithione. It is structurally similar to ciclopirox and pyrithione, containing a substituted pyridine (pyridinone) group which inhibits ergosterol synthesis.

Product Details:

Ranolazine is used to treat chronic angina (chest pain). This medicine is usually used together with other medicines (eg, ACE inhibitors, angiotensin receptor blockers, calcium channel blockers, beta-blockers, nitrates, antiplatelets, or lipid-lowering medicines).

Product Details:

A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic. For the prevention and reversal of bronchospasm in patients 12 years of age and older with reversible, obstructive airway disease, as well as symptomatic management of reversible bronchospasm associated with bronchitis and emphysema. Also used acute IV and sub-Q therapy in selected women to inhibit uterine contractions in preterm labor (tocolysis) and prolong gestation when beneficial.

Synonyms:

• Terbul; Convon; Brethine; Monovent; Bricanyl; Brithine; Butalire; Butaliret; Terbasmin; Brethaire

Product Details:

Crystalline Powder, having no more than a slight, but unpleasant odour.

 

Synonyms:

• Rate, Stereoisomer; Triprolidine Hcl Usp; Trans-Triprolidinehcl; Tripolidine Hydrochloride; Triprolidine Hydrochloride; Triprolidine Hcl Monohydrate; Triprolidinehydrochloride,Usp; Triprolidinesigmareferencestandard; Triprolidine Hydrochloride (500 Mg); Triprolidine Hydrochloride (300 Mg)

Product Details:

Clear to pale yellow liquid

 

Application:

• Used as antifoaming and surface active agent. As its sulfo – succinate derivative it is used in anti-dandruff shampoos.

Product Details:

This compound belongs to the biphenyltetrazoles and derivatives. These are organic compounds containing a biphenyl attached to a tetrazole. A carbon atom of the biphenyl moiety is boned to a carbon or the nitrogen atom of the tetrazole moiety.

 

Application:

• May be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.

Product Details:

A nasal vasoconstricting decongestant drug which acts by binding to the same receptors as adrenaline. It is applied as a spray or as drops into the nose to ease inflammation and congestion of the nasal passageways. It binds alpha-adrenergic receptors to activate the adrenal system which causes systemic vasoconstriction, thereby easing nasal congestion.

 

Synonyms:

• Olynth; Novorin; Xymelin; Brizolin; Therapin; Galazolin; Neo-Rinoleina; Xylonetazolinehcl; Neo-Ii; Xylometazoline HCL

Product Details:

White to slightly pink powder.

 

Synonyms:

• 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one Hydrochloride Monohydrate

 

IUPAC Name:

• 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one hydrate hydrochloride

Product Details:

Cyclophosphamide is indicated for the treatment of malignant lymphomas, multiple myeloma, leukemias, mycosis fungoides (advanced disease), neuroblastoma (disseminated disease), adenocarcinoma of the ovary, retinoblastoma, and carcinoma of the breast. It is also indicated for the treatment of biopsy-proven minimal change nephrotic syndrome in pediatric patients

Synonyms:

• Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate

Product Details:

An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Product Details:

This compound belongs to the aminocyclitols and derivatives. These are cyclitols with at least one hydroxyl group replace by an amino group.

 

Synonyms:

Voglibose; 3,4-Dideoxy-4-[[2-Hydroxy-1-(Hydroxymethyl)Ethyl]Amino]-2-C-(Hydroxymethyl)-D-Epiinositol; 3,4-Dideoxy-4-[[2-Hydroxy-1-(Hydroxymethyl)Ethyl]Amino]-2-C-(Hydroxymethyl)-D-Epinositol; 5-(1,3-Dihydroxypropan-2-Ylamino)-1-(Hydroxymethyl)Cyclohexane-1,2,3,4-Tetrol;Voglibose, 99+%; A 71100; Ao 128;Basen

 

Application:

• For the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.

Product Details:

Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures. Zonisamide may be a carbonic anhydrase inhibitor although this is not one of the primary mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels leading to a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of the inhibitory neurotransmitter GABA while enhancing the uptake of the excitatory neurotransmitter glutamate.

Synonyms:

• ZON; ci-912; ad-810; pd110843; excegram; exceglan; Excegran; Zonegran; Excemide; Zonisamide

Additional Information:

• Packaging Details: Hdpe Drum

Product Details:

Doxorubicin hydrochloride is a DNA intercalator and powerful cytotoxic agent. Once it associates with the DNA groove, a covalent linkage forms between a DNA base and the pendant sugar of the small molecule. The intercalation into DNA blocks the replication of DNA by blocking Topo II (Topoisomerase II) This general mechanism gives it efficacy in a wide range of different cell types. Additionally, the expression of the oncogenes c-Myc and c-Jun is also down regulated by the chemical and a significant correlation was reported between the level of expression of these genes and the degree of cell growth inhibition conferred by Doxorubicin. Doxorubicin hydrochloride is an inhibitor of AMPK, TERT and POLR.

Synonyms:

• Dox; Adr; Caely; Caelyx; Fi6804; Fi 106; Dox Hcl; Lipodox; Adriacin; Ardriamycin

Product Details:

Mupirocin Calcium is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl tRNA synthase. With excellent activity against gram-positive staphylococci and streptococci, it is primarily used for treatment of primary and secondary skin disorders, nasal infections, and wound healing.

MUPIROCIN CALCIUM USP JAIRADHESALES

Product Details:

Tazarotene (marketed as Tazorac, Avage and Zorac) is a prescription topical retinoid sold as a cream or gel. This medication is approved for treatment of psoriasis, acne, and sun damaged skin (photodamage).

Synonyms:

• Zorac; Tazorac; agn190168; TAZAROTENE; Tazorac/zorac; Tazarotene(Avage); Tazarotene 99% Min; 6-[2-(3,4-Dihydro-4,4-diMethyl-2H-1-benzothiopyran-6-yl)ethynyl]-; ethyl 6-[2-(4,4-dimethylthiochroman-6-yl)ethynyl]pyridine-3-carboxylate; 3-pyridinecarboxylicacid,6-((3,4-dihydro-4,4-dimethyl-2h-1-benzothiopyran-6-y