Jai Radhe Sales

Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. It is marketed by Pfizer under the brand name Celebrex. In some countries, it is branded Celebra. Celecoxib is available by prescription in capsule form.

Synonyms:

• Celebrex;Celecoxib; 4-[[5-(4-Methylphenyl)-3-Trifluoromethyl]-1H-Pyrazol-Yl] Benzenesulfonamide; 4-[5-((4-Methylphenyl)-3-Trifluorpmethyl)-1H-Pyrazol-Yl] Benenesulfonamide; Celecoxib, 4-[5-(4-Methylphenyl)-3-Trifluoromethyl)-1H-Pyrazol-Yl] Benzenesulfonamide; Benzenesulfonamide, 4-5-(4-Methylphenyl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl-;4-[5-(4-Methylphenyl)-3-(Trifluoromethyl)Pyrazol-1-Yl] Benzenesulfonamide;Celebra

 

Application:

• For relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis

Mepyramine is a histamine H1 receptor antagonist and binds with high affinity to G(q/11) protein. Mepyramine maleate is found to be a potent inhibitor of CYP2D6 (P450 2D forms) in hepatocytes, and PAF-induced platelet aggregation. Mepyramine is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. This product has been recently discovered to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.

Synonyms:

• Mepyramine maleate;Pyrilamine Maleate;N-(4-methoxybenzyl)-N',N'-dimethyl-N-(pyridin-2-yl)ethane-1,2-diamine;N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine (2Z)-but-2-enedioate;N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine (2E)-but-2-enedioate

 

IUPAC Name:

• (Z)-but-2-enedioic acid; N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine

 

MEPYRAMINE MALEATE JAIRADHE SALES