Active Pharmaceutical Ingredients

Product Details:

Terbinafine Hydrochloride is a synthetic allylamine derivative structurally related to naftifine, antifungal Terbinafine Hydrochloride blocks ergosterol biosynthesis by inhibition of squalene epoxidase, part of the sterol synthesis pathway for the fungal cell membrane. Highly lipophilic, it tends to accumulate in skin, nails, and fatty tissues. Terbinafine is active against dermatophytes. (NCI04)

IUPAc name - (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine;hydrochloride

Product Details:

A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.

Product Details:

A cardioselective beta-adrenergic blocker possessing properties and potency similar to propranolol, but without a negative inotropic effect. This compound belongs to the phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring.

Synonyms:

• Noten;Unilo;Altol;Ateni;Seles;Xaten;tenlol;atenol;uniloc;Alinor

Product Details:

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient’s immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.

Synonyms:

• FK-506; prograf; fr900506; L 679934; Protopic; Advagraf; Fujimycin; TacroBell; TACROLIMUS; FK-506, 99+%

Application:

• For use after allogenic organ transplant to reduce the activity of the patient''s immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart, small bowel, pancreas, lung, trachea, skin, cornea, and limb transplants. It has also been used in a topical preparation in the treatment of severe atopic dermatitis.

IUPAC Name:

• (1R,9S,12S,13R,14S,17R,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone

Product Details:

Triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS

Synonyms:

• Fluconazole Impurity C;Fluconazole Related Compound C;fluconazole related substance EP C; fluconazole related substance USP C;1,1'-(1,3-phenylene)di-1H-1,2,4-triazole;1,1'-(1,3-Phenylene)bis-1H-1,2,4-triazole

Product Details:

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.

Product Details:

Cetrimide is used as an active pharmaceutical ingredient (API), an antispetic agent with detergent properties. It has the wide spectrum of antiinfectives against bacteria and fungi. It is used as an ingredient of shampoos for treatingseborrhoea and psoriasis. A very dilute solution can be applied topically for the relief of sore gums.

Synonyms:

• TTAB; MTAB; mytab; MitMAB; morpant; Cetrimide; tetradonium; quaternium13; MicrocideIitm; Tetradoniumbromid

Product Details:

Torsemide is used to help treat fluid retention (edema) and swelling that is caused by congestive heart failure, liver disease, kidney disease. It belongs to the group of medicines called loop diuretics (water pills). This medicine works by acting on the kidneys to increase the flow of urine.

Product Details:

An almost colourless, or pale-yellowish liquid.

Synonyms:

• Abacil; D00858;d-)(2:1; hibidil; placout; septeal; unisept; corsodyl; disteryl; orahexal

Product Details:

Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It may improve your mood and energy level and may help restore your interest in daily living.

Product Details:

Rizatriptan is used to treat acute migraine headaches in adults and children 6 years of age and older. It is not used to prevent migraine headaches and is not used for cluster headaches. Rizatriptan works in the brain to relieve the pain from migraine headaches. It belongs to the group of medicines called triptans

Product Details:

Montelukast Sodium is a potent, selective, anti-inflammatory CysLT1 receptor antagonist (IC50 < 5nM) with no appreciable affect on the CysLT2 receptor. In rat colitis Montelukast Sodium has demonstrated the ability to increase PGE2 (Prostaglandin E2 - sc-201225) production and lower COX-2 expression. Inhibition is competitive with respect to leukotrienes - particularly LTD4, a biologically active mediator that plays an important role in the control of several biochemical pathways involving pulmonary and immune system function.

Synonyms:

• mk-476; MK-476-d6; ingulair; Montelukast Na; Mk-476, Singulair; Motelukast Sodium; Montelukst Sodium; Montelukast Sodium; Montelukast Soudium; Montelukast Sodium USP

 

IUPAC Name:

• Sodium 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate

Additional Information:

• Production Capacity: 500kg

Product Details:

A White or Pale Yellow crystalline powder. Odorless

 

Synonyms:

• Emetiral; Vertigon; buccastem; nibromina; pasotomin; enedioate(1:2); meterazinmaleate; Einecs 201-511-3; stemetildimaleate; Prochlorperazine Maleate

Product Details:

A clear or almost clear liquid or a solid crystalline mass, colourless or slightly yellow when freshly prepared, which darkens on keeping; odour, characteristic. Amylmetacresol should be protected from light.

Application:

• Amylmetacresol is an antiseptic used to treat minor infections of the mouth and throat. It is one of two active ingredients in Gorpils lozenges or Strepsils. Boots Group or Gepach International also make a lozenge with this as active ingredient.

Product Details:

Betamethasone topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. This medicine is a corticosteroid

Synonyms:

• Betamethasone Dipropionate Mm(Crm Standard);Betamethasone Dipropionate Usp(Crm Standard)

Product Details:

Betamethasone 21-phosphate sodium salt is a corticosteroid with anti-inflammatory and immunosuppressive abilities. Betamethasone 21-phosphate sodium salt is used where water retention is undesirable.

Synonyms:

• Betamethasone 21-phosphate disodium; bentelan; betamethasonedisodiumphosphate

Product Details:

Candesartan is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Candesartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so blood can flow more easily.

Product Details:

Carbinoxamine is used to treat symptoms of seasonal (short-term) or perennial (long-term) allergies, such as sneezing, runny nose, itching, watery eyes, hives, skin rash, itching, or wheezing

Product Details:

Tenofovir disoproxil, , is a medication used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. It is generally recommended for use with other antiretrovirals

Product Details:

TETRACYCLINE HYDROCHLORIDE

CAS # 64-75-5

Tetracycline HCl

Achromycin hydrochloride

Tetracycline.HCl

Product Details:

Aceclofenac belongs to a group of Non Steroidal Anti-inflammatory Drugs (NSAIDs) used to treat various painful inflammatory conditions. The mode of action of aceclofenac is largely based on the inhibition of prostaglandin synthesis. Aceclofenac is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandins. The Drugs inhibits synthesis of the inflammatory cytokines interleukin (IL)-1 and tumor necrosis factor and prostaglandin E2 (PGE2) production.

Synonyms:

• 2-(2-(2-(2,6-dichlorophenyl)aminophenyl)acetyl)oxyacetic acid, 2-((2,6-dichlorophenyl)amino)-benzeneacetic acid carboxymethyl ester, [({2-[(2,6 dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid.

Application: Relief of pain and inflammation

Product Details:

White to off white crystalline powder

Synonyms:

• Ly 139603; Strattera; Atomoxetine; Atomoxitine; Atomoxetine Hcl; Atomoxetine Hci; Atomoxitine Hcl; Tomoxetine Hydrochloride; Atomoxetine Hydrochloride; R-Tomexetine Hydrochloride

Product Details:

Alendronate is a nitrogen-containing, second generation bisphosphonate. Bisphosphonates were first used to treat Paget’s disease in 1971. This class of medications is comprised of inorganic pyrophosphate analogues that contain non-hydrolyzable P-C-P bonds. Similar to other bisphosphonates, alendronate has a high affinity for bone mineral and is taken up during osteoclast resorption. Alendronate inhibits farnesyl pyrophosphate synthetase, one of the enzymes in the mevalonic acid pathway involved in producing isoprenoid compounds that are essential for post-translational modification of small guanosine triphosphate (GTP)-binding proteins, such as Rho, Ras and Rab. Inhibition of this process interferes with osteoclast function and survival. Alendronate is used for the treatment of osteoporosis and Paget’s disease.

Synonyms:

• G-704650; Alendronate Sodium Salt; Alendronate, Sodium Salt Trihydrate; Alendronate Sodium Trihydrate;Alendronnate Sodium Trihydrate; Alendronic Acid, Monosodium Salt, Trihydrate; Adronat; 4-Amino-1-Hydroxybutylidine-1,1-Bisphosphonate Sodium Salt Trihydrate

Product Details:

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.

Application:

• Ambroxol is indicated as “secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breathe freely and deeply.

 

Synonyms:

• Mucosolvan; Ambroxol Hcl; Ambroxolhydrocloride; Ambroxolhydrochlo ride(Ep2001/Cp2000); Trans-4-((2-Amino-3,5-Dibromobenzyl) Amino) Cyclohexanol, Hcl;4-[(2-Amino-3,5-Dibromo-Benzyl) Amino] Cyclohexanol Hydrochloride; 4-[(2-Amino-3,5-Dibromophenyl)Methylamino] Cyclohexan-1-Ol Hydrochloride; 4-[(2-Azanyl-3,5-Dibromo-Phenyl) Methylamino] Cyclohexan-1-Ol Hydrochloride;2-Amino-3,5-Dibromo-N-[Trans-4-Hydroxycyclohexyl] Benzylamine Hydrochloride;Trans-4-[[(2-Amino-3,5-Dibromophenyl)Methyl] Amino] Cyclohexanol Monohydrochloride

Product Details:

Cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.

Synonyms:

• Bactigras; Arlacide A; 10,040Diacetate; Hibitaneacetate; Hibitane Diacetate; Chlorhexidinecitrate; Chlorhexidine Diacet; Chlorhexidine Acetate; Chlorhexidine Acatate; Chlorohexidine Acetate

Product Details:

Artesunate is a derivative of artemisinin and belongs to a class with antimicrobial properties. The compound is an active ingredient in the Chinese herb Artemisia annua and has been used in Malaria studies. Artesunate has been tested against 55 cell lines and demonstrated anti-cancer activity. Research shows that conditional expression of CDC25A heightens the sensitivity of tumor cells to artesunate.

Synonyms:

• AsuMax; Cosunate; Saphnate; WR-256283; ARTESUNATE; PlasMotriM; PlasMotrin; Qinghaozhi; Vartesunate; Arteannuinum

Product Details:

This compound belongs to the gluco/mineralocorticoids, progestogins and derivatives. These are steroids whose structure is based on an hydroxylated prostane moiety.

Synonyms:

• bp2; QVAR; kw-053; Viarex; Viarox; aldecin; Aerobec; Anceron; Beclate; beclacin

Product Details:

A White or almost white, crystalline powder, sparingly soluble in water and in propylene glycol, very slightly soluble in alcohol

Synonyms:

• CHX;U-4527; LISIUM; NSC-185;ay 5312; ACTIDION; ACTIDONE; ACTI-AID; ArlacideH; ANTI-DIONE

Product Details:

Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties.

Synonyms:

• Zylate; Scabide; ASCABIN; Benylate; Colebenz; Scabagen; Scabanca; Scabitox; Scobenol; Vanzoate

Product Details:

Ramipril is an inhibitor of the ACE (angiotensin- converting enzyme) that is reported to quickly hydrolyze into the active metabolite Ramiprilat. Studies indicate that Ramipril is a more potent inhibitor in comparison to Zofenopril (sc-208496). Acute coronary syndrome investigations demonstrate that Ramipril increases IL-10, and decreases the levels of MCP-1 and IL-18.

Synonyms:

• [2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclo-penta[b]pyrrole-2-carboxylic acid

IUPAC Name:

• (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid

Product Details:

White crystalline or amorphous powder, having a faint odour suggestive of burnt sugar.

Synonyms:

• levucal;flanthin; mil-u-cal; laevucalcin; levulincalcid; Calciumlevulate; calciumpharmacon; LCIUM LEVULINATE; calcium-diasporal; calcium laevulate

Product Details:

A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.Allopurinol is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.

Product Details:

Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.

Synonyms:

• 1,8-Diethyl-1,3,4,9-Tetrahydropyrano[3,4-B]Indole-1-Acetic Acid

Application:

• For acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.

Product Details:

Adapalene is a retinoic acid analog that is a RARβ and RARγ agonist (AC50 values are 2.2, 9.3, 22 and > 1000 nM for RARβ, RARγ, RARα and RXRα receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cells in vitro.

Synonyms:

• ADAPALENE;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHALENE CARBOXYLIC ACID;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID;6-[3-(1-adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid;Adapalen;6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid;CD-271;Differi

Product Details:

Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients

 

Synonyms:

• cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-d8

 

Application:

• For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.

 

IUPAC Name:

• 1-[4-(4-{[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one

Product Details:

Anthelmintic used in grazing animals for fasciola and cestode infestations.

IUPAc name - 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide

Product Details:

Calcipotriol is a synthetic vitamin D3 analog that binds to vitamin D receptors in epidermal cells. In vitro studies have shown that calcipotriol stimulates terminal cell differentiation and has antiproliferative effects. In vivo, calcipotriol has been shown to reduce the number of cycling epidermal cells.

Additional Information:

• Production Capacity: 1Kg
• Delivery Time: Immediate

Product Details:

Cilostazol improves the flow of blood through the blood vessels. It is used to reduce leg pain caused by poor circulation (intermittent claudication). Cilostazol makes it possible to walk farther before having to rest because of leg pain.

Additional Information:

• Production Capacity: 1000kg

Product Details:

(R)-(+)-Bupivacaine Hydrochloride is a local anaesthetic used for epidural and intrathecal anaesthesia.

Synonyms:

• 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide

Product Details:

Biperiden hydrochloride is a muscarinic receptor (mAChR M) antagonist that displays some selectivity for the mAChR M1 subtype (Ki values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for mAChR M1, mAChR M4, mAChR M3, mAChR M2 and mAChR M5 receptors, respectively)

Synonyms:

• Bicamol; Akiriden; Tasmolin; NSC 84989; NSC 170950; BIPERIDINE HCL; Biperidene HCL; akinetonhydrochloride; BIPERIDEN HYDROCHLORIDE; biperidinehydrochloride